04660nam 22007095 450 991025388150332120231222115554.03-319-22708-410.1007/978-3-319-22708-5(CKB)3710000000501083(EBL)4089850(SSID)ssj0001583910(PQKBManifestationID)16264363(PQKBTitleCode)TC0001583910(PQKBWorkID)14865656(PQKB)11339854(DE-He213)978-3-319-22708-5(MiAaPQ)EBC4089850(PPN)190520280(EXLCZ)99371000000050108320151103d2016 u| 0engur|n|---|||||txtccrSynthetic Biology /edited by Anton Glieder, Christian P. Kubicek, Diethard Mattanovich, Birgit Wiltschi, Michael Sauer1st ed. 2016.Cham :Springer International Publishing :Imprint: Springer,2016.1 online resource (371 p.)Description based upon print version of record.3-319-22707-6 Includes bibliographical references at the end of each chapters and index.Xenobiotic life (artificial cells and cell like structures, biological nanostructures, XNA) -- Novel DNA and RNA (synthetic promoters, riboswitches, small RNAs, ribozymes, adaptamers, DNA walker, DNA machines) -- Expansion of the genetic code and protein building blocks (orthogonal mRNA-ribosome pairs, non canonical amino acids) -- DNA logics and circuit design (including sensors, TALORs, genome rewiring repressilator, oscillator, metabolator, „Multicellular circuits“) -- Protein engineering (directed evolution, domain engineering) -- Synthetic metabolic pathways (engineered pathways, non natural pathways, scaffolding) -- Reengineered chassis cells (minimal organisms, platform hosts, minimal genomes, synthetic genomes) -- In silico simulation and design of complex metabolic and signalling networks -- Novel synthetic biomaterials -- Key methods for synthetic biology (assembly technologies, genome engineering technologies, DNA synthesis, Standardization) -- Public awareness and risk management.The emerging field of synthetic biology employs biotechnological approaches to recreate and enhance basic biological structures, intracellular processes and whole organisms. This book provides a comprehensive, up-to-date overview of the opportunities and challenges of this complex field of biotechnology, which combines various scientific disciplines. It addresses a broad range of topics, including redesigning complex metabolic pathways, DNA/RNA and protein engineering, as well as novel synthetic biomaterials. It discusses both “bottom up” and “top down” approaches and presents the latest genome engineering tools with predictions about how these could change our way of thinking and working. Since the use of synthetic biology raises a number of ethical questions, a chapter is devoted to public awareness and risk management. The book is of interest to scientists from both academia and industry, as well as PhD students and postdocs working in the field.Systems biologyBiochemical engineeringBiomaterialsGenetic engineeringSystems Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L15010Biochemical Engineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/C12029Biomaterialshttps://scigraph.springernature.com/ontologies/product-market-codes/Z13000Genetic Engineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/C12037Systems biology.Biochemical engineering.Biomaterials.Genetic engineering.Systems Biology.Biochemical Engineering.Biomaterials.Genetic Engineering.570660.6Glieder Antonedthttp://id.loc.gov/vocabulary/relators/edtKubicek Christian Pedthttp://id.loc.gov/vocabulary/relators/edtMattanovich Diethardedthttp://id.loc.gov/vocabulary/relators/edtWiltschi Birgitedthttp://id.loc.gov/vocabulary/relators/edtSauer Michaeledthttp://id.loc.gov/vocabulary/relators/edtBOOK9910253881503321Synthetic Biology1413076UNINA