03784nam 22006255 450 991025387120332120200702000254.01-4939-3612-310.1007/978-1-4939-3612-0(CKB)3710000000653419(EBL)4517675(SSID)ssj0001665634(PQKBManifestationID)16455007(PQKBTitleCode)TC0001665634(PQKBWorkID)15000417(PQKB)10119658(DE-He213)978-1-4939-3612-0(MiAaPQ)EBC4517675(PPN)193442450(EXLCZ)99371000000065341920160429d2016 u| 0engur|n|---|||||txtccrMitochondria and Cell Death[electronic resource] /edited by David M. Hockenbery1st ed. 2016.New York, NY :Springer New York :Imprint: Humana,2016.1 online resource (240 p.)Cell Death in Biology and Diseases,2625-2902Description based upon print version of record.1-4939-3610-7 Includes bibliographical references at the end of each chapters and index.Preface -- 1.Lethal and non-lethal functions of the permeability transition pore -- 2.Mitochondrial Calcium and Ischemia-Reperfusion Injury in Heart -- 3.Mislocalization of mitochondrial intermembrane space proteins -- 4.Bcl-2 protein interplay on the outer mitochondrial membrane -- 5.Remodeling of Mitochondria in Apoptosis -- 6.Physiologic and Pathologic Functions of Mitochondrial ROS -- 7.Mitochondrial Mutagenesis in Cancer -- 8.Mitochondrial UPR in cancer -- 9.Mitochondrial signaling -- 10.Mitochondria and antiviral immunity -- 11.Mitochondrial permeabilization from lethality to vitality -- Index.This volume examines the role of mitochondria in different types of cell death, including apoptotic and necrotic cell deaths. Topics discussed include mitochondrial outer membrane permeabilization (MOMP) and the permeability transition pore; core processes such as calcium handling, fission and fusion, reactive oxygen species generation, and maintenance of mitochondrial DNA fidelity and protein folding homeostasis; and retrograde signaling between mitochondria and other cellular components, including the important role of mitochondria in antiviral immunity. The expertly authored chapters are drawn from multidisciplinary international perspectives, lending a nuanced and comprehensive approach to the material. Mitochondria and Cell Death, part of the Cell Death in Biology and Diseases series, is invaluable reading for graduate students, researchers, and clinicians in the fields of neuroscience, oncology, gastroenterology, and hepatology, as well as those interested in the study of mitochondria and cell biology.Cell Death in Biology and Diseases,2625-2902ApoptosisCell membranes Cell cycleApoptosishttps://scigraph.springernature.com/ontologies/product-market-codes/L16060Membrane Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16050Cell Cycle Analysishttps://scigraph.springernature.com/ontologies/product-market-codes/L16030Apoptosis.Cell membranes .Cell cycle.Apoptosis.Membrane Biology.Cell Cycle Analysis.570Hockenbery David Medthttp://id.loc.gov/vocabulary/relators/edtBOOK9910253871203321Mitochondria and Cell Death2536185UNINA