03437nam 22006495 450 991025386720332120200705033315.03-319-33145-010.1007/978-3-319-33145-4(CKB)3710000000649253(EBL)4513933(SSID)ssj0001665611(PQKBManifestationID)16455476(PQKBTitleCode)TC0001665611(PQKBWorkID)15000313(PQKB)11612035(DE-He213)978-3-319-33145-4(MiAaPQ)EBC4513933(iGPub)SPNA0044191(PPN)193445549(EXLCZ)99371000000064925320160423d2016 u| 0engur|n|---|||||txtccrAutophagy at the Cell, Tissue and Organismal Level /by Eleftherios Karanasios, Nicholas T. Ktistakis1st ed. 2016.Cham :Springer International Publishing :Imprint: Springer,2016.1 online resource (107 p.)SpringerBriefs in Cell Biology,2625-3534Description based upon print version of record.3-319-33143-4 Includes bibliographical references at the end of each chapters.Autophagy (Autophagia) from 1860 to 1963 -- History of Autophagy after 1963 -- Signalling in Autophagy -- Autophagosome Formation -- Physiological Role of Autophagy and Implications in Disease -- Studying autophagy: List of useful antibodies produced via a community effort.This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.SpringerBriefs in Cell Biology,2625-3534Cell biologyImmunologyBiochemistryCell Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16008Immunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Animal Biochemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/L14013Cell biology.Immunology.Biochemistry.Cell Biology.Immunology.Animal Biochemistry.570Karanasios Eleftheriosauthttp://id.loc.gov/vocabulary/relators/aut1062224Ktistakis Nicholas Tauthttp://id.loc.gov/vocabulary/relators/autBOOK9910253867203321Autophagy at the Cell, Tissue and Organismal Level2523557UNINA