03305nam 22006135 450 991025386090332120200705025330.03-319-27347-710.1007/978-3-319-27347-1(CKB)3710000000616284(EBL)4452729(OCoLC)945613280(SSID)ssj0001653366(PQKBManifestationID)16433198(PQKBTitleCode)TC0001653366(PQKBWorkID)14982712(PQKB)10235240(DE-He213)978-3-319-27347-1(MiAaPQ)EBC4452729(PPN)192774166(EXLCZ)99371000000061628420160315d2016 u| 0engur|n|---|||||txtccrClinical Pharmacology: Current Topics and Case Studies /edited by Markus Müller2nd ed. 2016.Cham :Springer International Publishing :Imprint: Springer,2016.1 online resource (398 p.)Description based upon print version of record.3-319-27345-0 Includes bibliographical references and index.The discipline of Clinical Pharmacology -- Current issues in drug development -- Current issues in drug regulation -- Current issues in drug reimbursement -- Ethics of clinical research -- GCP, Scientific misconduct -- Phases of drug development, first in man studies -- Clinical trials - Interventional studies -- Clinical trials - observational studies -- Imaging -- Microdosing -- Genomics -- Pharmacokinetics/Pharmacodynamics -- Epidemiology, statistics -- Placebo effects -- Pharmaceutical drug safety -- Drug interactions -- Advanced therapies -- Biological pharmaceuticals -- Generic drugs, Enantiomers -- Special situations I: orphan drugs -- Special situations II: sex differences -- Special situations III: children.This revised and extended second edition focuses on current and emerging topics in drug development, their molecular mechanisms of action as well as regulatory issues. In addition, in-depth insights into clinical drug research and trial methodology are presented on the basis of concrete case studies. This updated book makes a valuable contribution to the field of Clinical Pharmacology and serves as a must-have guide for professors, researchers and advanced students from academia and pharmaceutical industry. .PharmacologyPharmacyPharmacotherapyPharmacology/Toxicologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B21007Pharmacyhttps://scigraph.springernature.com/ontologies/product-market-codes/F00008Pharmacotherapyhttps://scigraph.springernature.com/ontologies/product-market-codes/H69000Pharmacology.Pharmacy.Pharmacotherapy.Pharmacology/Toxicology.Pharmacy.Pharmacotherapy.610Müller Markusedthttp://id.loc.gov/vocabulary/relators/edtBOOK9910253860903321Clinical Pharmacology: Current Topics and Case Studies2526692UNINA