05545oam 2200481I 450 991016388190332120230810002110.01-315-27817-01-315-27815-41-315-27816-210.1201/b21922 (CKB)3710000001051154(MiAaPQ)EBC4799803(OCoLC)971586286(EXLCZ)99371000000105115420180417d2017 uy 0engurcnu||||||||rdacontentrdamediardacarrierImaging in photodynamic therapy /edited by Michael R. Hamblin, Yingying HuangFirst edition.Boca Raton, FL :Routledge, an imprint of Taylor and Francis,2017.1 online resource (502 pages) color illustrations, tablesSeries in Cellular and Clinical Imaging1-4987-4145-2 Includes bibliographical references at the end of each chapters and index.part PART 1INTRODUCTION -- chapter 1 Looking out the optical window: Physical principles and instrumentation of imaging in�photodynamic therapy /Hui Liu -- chapter 2 Photochemistry and photophysics of PDT and�photosensitizers /Marcin Ptaszek -- part PART 2 IN VITRO MICROSCOPY FOR PHOTOSENSITIZER LOCALIZATION IN CELLS -- chapter 3 Phthalocyanines in photodynamic therapy /Heidi Abrahamse -- chapter 4 Singlet oxygen luminescence imaging: A prospective tool in bioscience? /Michael Pfitzner, Jan C. Schlothauer, Lisheng Lin, Buhong�Li, and Beate R�der -- chapter 5 Microbial biofilms and antimicrobial photodynamic therapy /Anil Kishen -- chapter 6 High-content imaging for photosensitizer screening /Gisela M.F. Vaz, Mathias O. Senge, Sarah-Louise Ryan, and�Anthony Davies -- part PART 3: IN VITRO MICROSCOPY OF CELL DAMAGE AND DEATH PROCESSES AFTER�PDT -- chapter 7 Enhanced efficacy of photodynamic therapy via an iron�lysosome�mitochondria connection: Studies with phthalocyanine 4 /Anna-Liisa Nieminen, Hsin-I Hung, and John J. Lemasters -- chapter 8 Role of cell death pathways in response to photodynamic therapy in gliomas /Leonardo Barcelos de Paula, Fernando Lucas Primo, and�Antonio Claudio Tedesco -- chapter 9 In search of specific PDT photosensitizers: Subcellular localization and cell death pathways /Tayana M. Tsubone, Christiane Pavani, Isabel O.L. Bacellar, and Maur�cio S. Baptista -- part PART 4 THERANOSTIC AGENTS AND NANOTECHNOLOGY -- chapter 10 Quantum dots in PDT -- chapter 11 Tetrapyrrole-based theranostic combinations of photodynamic action and magnetic resonance imaging /Duygu Aydin Tekdas, Devrim Atilla, Vefa Ahsen, and Ays�e G�l G�rek -- chapter 12 Theranostic applications of photodynamic molecular beacons /Wentao Song -- chapter 13 Tumor-specific imaging and photodynamic therapy targeting the urokinase receptor /Zafar Iqbal, Longguang Jiang, Zhuo Chen, Cai Yuan, Rui Li, Ke Zheng, Xiaolei Zhou, Jincan Chen, Ping Hu, and�Mingdong Huang -- part PART 5 SMALL ANIMAL IMAGING -- chapter 14 Vascular imaging in photodynamic therapy /Bin Chen -- chapter 15 Photosensitizer activity imaging on the microscopic scale /Steffen Hackbarth -- chapter 16 Bioluminescence imaging for monitoring the effectiveness of photodynamic therapy for infections in animal models /Pawel Mroz -- part PART 6 CLINICAL IMAGING -- chapter 17 Imaging of photosensitizers in skin /Marica B. Ericson -- chapter 18 Brain tumor imaging with ALA /Herbert Stepp -- chapter 19 PDT of non-muscle-invasive bladder cancer with Hexylester Aminolevulinate: Optimization of the illumination wavelengths by fluorescence spectroscopy and imaging /Matthieu Zellweger -- chapter 20 Endoscopic imaging and photodynamic therapy /Harubumi Kato, Kinya Furukawa, Yasufumi Kato, Jitsuo Usuda, Kuniharu Miyajima, and�Keishi Ohtani -- chapter 21 Spectroscopic imaging in prostate PDT /Rozhin Penjweini -- chapter 22 Fluorescent-guided resection in clinical oncology /Ron R. Allison.This book covers the broad field of cellular, molecular, preclinical, and clinical imaging either associated with or combined with photodynamic therapy (PDT). It showcases how this approach is used clinically for cancer, infections, and diseases characterized by unwanted tissue such as atherosclerosis or blindness. Because the photosensitizers are also fluorescent, the book also addresses various imaging systems such as confocal microscopy and small animal imaging systems, and highlights how they have been used to follow and optimize treatment, and to answer important mechanistic questions. Chapters also discuss how imaging has made important contributions to clinical outcomes in skin, bladder, and brain cancers, as well as in the development of theranostic agents for detection and treatment of disease. This book provides a resource for physicians and research scientists in cell biology, microscopy, optics, molecular imaging, oncology, and drug discovery.Series in cellular and clinical imaging.PhotochemotherapyPhotochemotherapy.615.831Hamblin Michael R.1166061Hamblin Michael R.Huang Ying-YingFlBoTFGFlBoTFGBOOK9910163881903321Imaging in photodynamic therapy2890058UNINA