03633nam 22005775 450 991016301460332120200701162737.03-319-48927-510.1007/978-3-319-48927-8(CKB)3710000001006641(DE-He213)978-3-319-48927-8(MiAaPQ)EBC4774358(PPN)197455875(EXLCZ)99371000000100664120161230d2017 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierTaste and Smell /edited by Dietmar Krautwurst1st ed. 2017.Cham :Springer International Publishing :Imprint: Springer,2017.1 online resource (XV, 199 p. 123 illus., 25 illus. in color.) Topics in Medicinal Chemistry,1862-2461 ;233-319-48925-9 Includes bibliographical references at the end of each chapters and index.Taste receptor gene expression outside the gustatory system -- Medicinal Chemistry of Plant Naturals as Agonists/Antagonists for Taste Receptors -- Chemical activation of TRP channels in taste and smell -- Olfactory transduction channels and their modulation by varieties of volatile substances -- Chemosensory G protein-coupled receptors (GPCR) in blood leukocytes -- Neuronal functions and emerging pharmacology of TAAR1.Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.Topics in Medicinal Chemistry,1862-2461 ;23Medicinal chemistryProteins PharmacologyMedicinal Chemistryhttps://scigraph.springernature.com/ontologies/product-market-codes/C28000Receptorshttps://scigraph.springernature.com/ontologies/product-market-codes/L14110Pharmacology/Toxicologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B21007Medicinal chemistry.Proteins .Pharmacology.Medicinal Chemistry.Receptors.Pharmacology/Toxicology.615.19Krautwurst Dietmaredthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910163014603321Taste and Smell1562247UNINA