04468nam 22008295 450 991043784780332120250327172258.09781299407657129940765X9789400755901940075590210.1007/978-94-007-5590-1(CKB)2670000000328600(EBL)1083596(OCoLC)827212343(SSID)ssj0000879298(PQKBManifestationID)11956564(PQKBTitleCode)TC0000879298(PQKBWorkID)10850613(PQKB)11078593(DE-He213)978-94-007-5590-1(MiAaPQ)EBC1083596(PPN)168341328(EXLCZ)99267000000032860020130202d2013 u| 0engur|n|---|||||txtccrMicroRNA Cancer Regulation Advanced Concepts, Bioinformatics and Systems Biology Tools /edited by Ulf Schmitz, Olaf Wolkenhauer, Julio Vera1st ed. 2013.Dordrecht :Springer Netherlands :Imprint: Springer,2013.1 online resource (350 p.)Advances in Experimental Medicine and Biology,2214-8019 ;774Description based upon print version of record.9789400755895 9400755899 Preface -- 1 MicroRNAs in human cancer -- 2 Bioinformatics, non-coding RNAs and its possible application in personalized medicine -- 3 MicroRNA target prediction and validation -- 4 MicroRNA-regulated networks: the perfect storm for classical molecular biology, the ideal scenario for systems biology -- 5 The p53/microRNA network in cancer: experimental and bioinformatics approaches.-6 MicroRNAs in melanoma biology -- 7 MicroRNA in the lung -- 8 The E2F1-miRNA cancer progression network -- 9 Modeling of microRNA-transcription factor networks in cancer -- 10 Coordinated networks of microRNAs and transcription factors with evolutionary perspectives -- 11 Mathematical modeling of microRNA-mediated mechanisms of translation repression -- 12 Web resources for microRNA research -- 13 Discovery of microRNA regulatory networks by integrating multidimensional high-throughput data -- 14 Discovering the functional microRNA-mRNA regulatory modules in heterogeneous data -- 15 Elucidating the role of microRNAs in cancer through data mining techniques -- 16 Working together: Combinatorial regulation by microRNAs.  .This book reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and their applications in combination with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. The use of high-throughput quantitative techniques makes an integrative experimental and computational approach necessary. This book will be a resource for researchers starting out with microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology, and the state-of-the-art in computational microRNA biology.Advances in Experimental Medicine and Biology,2214-8019 ;774CancerBioinformaticsMedicineResearchBiologyResearchMolecular geneticsCancer BiologyBioinformaticsComputational and Systems BiologyBiomedical ResearchMolecular GeneticsCancer.Bioinformatics.MedicineResearch.BiologyResearch.Molecular genetics.Cancer Biology.Bioinformatics.Computational and Systems Biology.Biomedical Research.Molecular Genetics.616.994042Schmitz Ulf1695053Wolkenhauer Olaf1966-895618Vera Julio1759221MiAaPQMiAaPQMiAaPQBOOK9910437847803321MicroRNA cancer regulation4197615UNINA02328nam 2200361z- 450 991016028870332120210112041720.097819094545451909454540(CKB)3710000001023409(MiAaPQ)EBC4782983(VLeBooks)9781909454545(Perlego)3892405(EXLCZ)99371000000102340920240607d2016 uy |engtxtrdacontentcrdamediacrrdacarrierIndependence Days The Story of UK Independent Record LabelsCherry Red Books1 online resource (577 p.)Drawing on more than 160 interviews with many of the most significant figures of the era, 'Independence Days' documents the UK independent record label boom from the late 1970s onwards.While many leading punk bands were co-opted by major labels, a new generation of independent spirits took the baton and revolutionised the course of popular music during a decade of artistic innovation and risk-taking…Even by the standards of Alex Ogg's previous work (The Hip Hop Years, No More Heroes), this is an exhaustive undertaking, providing a detailed overview of the history of independent labels in the UK, including Chiswick, Stiff, Rough Trade, Beggars Banquet, 4AD, Factory, Mute, Crass, Cherry Red and a myriad of smaller and boutique labels. Interviewees include Geoff Travis, Bill Drummond, Miles Copeland, Daniel Miller, Ivo Watts-Russell, Iain McNay, Dave Robinson, Ted Carroll, Roger Armstrong, Penny Rimbaud, Richard Boon, Martin Mills, Richard Scott, Mike Alway, Mike Stone, Bob Last, Terri Hooley, Bill Gilliam, Charlie Gillett, Seymour Stein, Geoff Davies and many more.From the budget DIY of Buzzcocks and the Desperate Bicycles to the chart dominance of Depeche Mode, New Order and the Smiths, all the key moments and the thoughts of its participants are documented through painstaking research, analysis and eyewitness accounts.Music tradeSound recording industryMusic trade.Sound recording industry.338.47781660941Ogg Alex1241059BOOK9910160288703321Independence days2879033UNINA