03397nam 2200481 450 991015743790332120180125150959.00-19-065126-10-19-065127-X0-19-065125-3(CKB)3710000001000650(MiAaPQ)EBC4773438(StDuBDS)EDZ0001615644(PPN)19951044X(EXLCZ)99371000000100065020170110h20172017 uy 0engurcnu||||||||rdacontentrdamediardacarrierImmunity the evolution of an idea /Alfred I. TauberNew York, NY :Oxford University Press,2017.1 online resource (329 pages)Previously issued in print: 2017.0-19-091419-X 0-19-065124-5 Includes bibliographical references and index.Cover; Immunity; Copyright; Dedication; Contents; Preface; Acknowledgments; Introduction; 1. A History of the Immune Self; 2. Whither Immune Identity?; 3. Individuality Revised; 4. Immune Cognition; 5. Eco-​immunology; 6. A New Biology?; Epilogue; Notes; References; IndexImmunology is the science of biological identity. Three key characteristics—individuality, identification, and immunity—together define immune identity, and as one notion changes meaning, so do the others. The story of this mutual dependence begins with the discovery of infectious diseases, when immunity, conceived as the response to invading pathogens, focused on the infected patient—later formalized as the “immune self.” That orientation, signifying autonomy much in line with cultural norms of individuality, dominated twentieth-century immune theory. Although an effective idiom, the self construct has proven inadequate to account for the organism’s normal physiology and exchanges with the environment. When integrated into its larger ecology, immunity’s governing model shifts from defense to the more basic cognitive function of information processing that discerns benign from the toxic. The effector function (assimilate or eliminate) only follows identification of the immune object. Moreover, as a cognitive–communicative system (analogous to the brain), the immune system’s various roles assume their full expression only when the organism is considered in its total environment—“internal” and “external.”From this perspective, beyond defending an insular individual, immunity accounts for the organism’s mutualist relationships that characterize the holobiont, where lines of demarcation are blurred. In response to this ecologically informed conception of the individual, the idea of immunity correspondingly widens. The implications of this revised configuration of immunity and its deconstructed notions of individuality and selfhood have wide significance for philosophers and life scientists working in immunology, ecology, and the cognitive sciences.ImmunologyPhilosophyImmunologyPhilosophy.616.07/9SCI075000MED044000bisacshTauber Alfred I.52944MiAaPQMiAaPQMiAaPQBOOK9910157437903321Immunity2597318UNINA