03299nam 2200445 450 991015525730332120210604083549.01-118-94063-61-118-94062-81-118-94064-4(CKB)4330000000007601(MiAaPQ)EBC4770361(DLC) 2016020707(EXLCZ)99433000000000760120170104h20172017 uy 0engurcnu||||||||rdacontentrdamediardacarrierBiosimilars of monoclonal antibodies a practical guide to manufacturing, preclinical, and clinical development /edited by Cheng Liu, K. John Morrow JrHoboken, New Jersey :Wiley,2017.©20171 online resource (723 pages) illustrations (some color)1-118-66231-8 Includes bibliographical references and index.The history of therapeutic monoclonal antibodies / Regis Sodoyer -- Structure, classification and naming of therapeutic monoclonal antibodies / Zhinan Xia -- Mechanism of action for therapeutic antibodies / Yu Zhou and James D. Marks -- Therapeutic monoclonal antibodies and their targets / Maurizio Chiriva-Internati, et al -- Antibody post-translational modifications / Roy Jefferis -- The pharmacology, pharmacokinetics, and pharmacodynamics of antibodies / Ningning Xu, Meimei Liu, Margaret Liu -- Monoclonal antibodies : applications in clinical oncology / Jeanene ("Gigi") Robison -- Development of biosimilar rituximab and clinical experience / Reena Nair -- Monoclonal antibodies for infectious diseases / Steven J. Projan -- Monoclonal antibodies for musculoskeletal, CNS, and other diseases / Junming Yie and Tao Wu -- Manufacture of recombinant therapeutic proteins using chinese hamster ovary cells in large-scale bioreactors : history, methods and perspectives / Florian M. Wurm and Maria De Jesus -- Process development / Samuel D. Stimple and David W. Wood -- Biosimilars and biobetters : impact on biopharmaceutical manufacturing and CMOs / Ronald A. Rader -- Cell line and cell culture development for biosimilar antibody drug manufacturing / Jianguo Yang -- Product analysis of biosimilar antibodies / Weidong Jiang, Scott Liu and Ziyang Zhong -- Bioanalytical development / Rafiq Islam -- Preclinical and clinical development of biosimilar antibodies / João Eurico Fonseca and João Gonçalves -- Regulatory issues / Clarinda Islam -- Legal considerations / K. Lance Anderson, Jennifer R. Moore Meline, and Jonathan D. Ball -- ADCC enhancement technologies for next generation therapeutic antibodies / Cheng Liu and Su Yan -- Biosimilar antibody half-life : engineering for optimal performance / K. John Morrow, Jr -- Technologies for antibody drug conjugation / Patrick G. Holder and David Rabuka.Monoclonal antibodiesDiagnostic useElectronic books.Monoclonal antibodiesDiagnostic use.574.293Liu ChengMorrow K. JohnJr.,MiAaPQMiAaPQMiAaPQBOOK9910155257303321Biosimilars of monoclonal antibodies2040266UNINA