02300oam 2200529I 450 991015488430332120240501170122.01-315-35536-11-315-37266-51-4822-4937-510.1201/9781315372662 (CKB)4340000000018631(MiAaPQ)EBC4751219(OCoLC)964698015(EXLCZ)99434000000001863120180331h20172017 uy 0engurcnu||||||||rdacontentrdamediardacarrierApplied surrogate endpoint evaluation methods with SAS and R /Ariel Alonso, Theophile Bigirumurame, Tomasz Burzykowski, Marc Buyse, Geert Molenberghs, Leacky Muchene, Nolen Joy Perualila, Ziv Shkedy, Wim Van der Elst1st ed.Boca Raton :CRC Press,[2017]©20171 online resource (396 pages) illustrationsChapman & Hall/CRC Biostatistics SeriesA Chapman and Hall book.1-4822-4936-7 Includes bibliographical references and index.I. Introductory material -- II. Contemporary surrogate endpoint evaluation methods : multiple-trial methods -- III. Software tools -- IV. Additional considerations and further topics.When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.Chapman & Hall/CRC biostatistics series.Clinical trialsStatistical methodsMedicineResearchMethodologyR (Computer program language)Clinical trialsStatistical methods.MedicineResearchMethodology.R (Computer program language)610.72Alonso Ariel(Statistician),FlBoTFGFlBoTFGBOOK9910154884303321Applied surrogate endpoint evaluation methods with SAS and R2172804UNINA