02702nam 2200517 450 991015320580332120200520144314.01-119-14318-71-119-14316-0(CKB)3710000000960605(MiAaPQ)EBC4751586(DLC) 2016034126(PPN)199264139(Au-PeEL)EBL4751586(CaPaEBR)ebr11307589(CaONFJC)MIL972905(OCoLC)965779136(EXLCZ)99371000000096060520160711h20172017 uy| 0engurcnu||||||||rdacontentrdamediardacarrierBasic pharmacokinetics and pharmacodynamics an integrated textbook and computer simulations /edited by Sara E. RosenbaumSecond edition.Hoboken, New Jersey :John Wiley & Sons, Incorporated,[2017]©20171 online resource (XIII, 552 pag.) ill1-119-14315-2 Includes bibliographical references and index.Introduction to pharmacokinetics and pharmacodynamics -- Passage of drugs through membranes -- Drug administration and drug absorption / Steven Sutton -- Drug distribution -- Drug elimination and clearance -- Compartmental models in pharmacokinetics -- Pharmacokinetics of an intravenous bolus injection in a one-compartment model -- Pharmacokinetics of an intravenous bolus injection in a two-compartment model -- Pharmacokinetics of extravascular drug administration / Steven Sutton -- Introduction to noncompartmental analysis -- Pharmacokinetics of intravenous infusion in a one-compartment model -- Multiple intravenous bolus injections in the one-compartment model -- Multiple intermittent infusions -- Multiple oral doses -- Nonlinear pharmacokinetics -- Introduction to pharmacogenetics -- Models used to predict drug-drug interactions for orally administered drugs -- Introduction to physiologically based pharmacokinetic modeling -- Introduction to pharmacodynamic models and integrated pharmacokinetic--pharmacodynamic models / Diane Mould and Paul Hutson -- Semi-mechanistic pharmacokinetic--pharmacodynamic model / Diane Mould and Paul Hutson.PharmacokineticsComputer simulationElectronic books.Pharmacokinetics.Computer simulation.615/.7Rosenbaum Sara(Sara E.),MiAaPQMiAaPQMiAaPQBOOK9910153205803321Basic pharmacokinetics and pharmacodynamics2241391UNINA