03728nam 2200649 a 450 991082993000332120230421044623.01-282-34796-997866123479620-470-51490-60-470-51491-4(CKB)1000000000377215(EBL)470445(OCoLC)609849343(SSID)ssj0000305463(PQKBManifestationID)11925006(PQKBTitleCode)TC0000305463(PQKBWorkID)10294237(PQKB)11001333(MiAaPQ)EBC470445(EXLCZ)99100000000037721520090715d1996 uy 0engur|n|---|||||txtccrP2 purionoceptors[electronic resource] localization, function and transduction mechanismsChichester Wiley19961 online resource (350 p.)Ciba Foundation symposium ;198Editors: Derek J. Chadwick (organizer) and Jamie A. Goode.Symposium held at Ciba Foundation, London, 11-13 July 1995.0-471-96125-6 P2 PURINOCEPTORS: LOCALIZATION, FUNCTION AND TRANSDUCTION MECHANISMS; Contents; Participants; P2 purinoceptors: historical perspective and cIassification; The diadenosine polyphosphate receptors: P2D purinoceptors; P2T purinoceptors: ADP receptors on platelets; P2Z purinoceptors; P2X receptors: a third major class of Iigand-gated ion channels; P2 purinoceptors and pyrimidinoceptors of catecholamine-producing cells and immunocytes; Trophic actions of extracellular ATP on astrocytes, synergistic interactions with fibroblast growth factors and underlying signal tranduction mechanismsTrophic roles of P2 purinoceptors in central nervous system astroglial cellsTransduction mechanisms of P2Z purinoceptors; The diverse series of recombinant P2Y purinoceptors; General discussion I; P2U purinoceptors: cDNA cloning, signal transduction mechanisms and structure-function analysis; Functional properties of native and cloned P2X receptors; ATP as a co-transmitter with no rad ren al i ne i n sym pat he t i c nerves-function and fate; ATP release and its prejunctional modulation; General discussion IIInvolvement of distinct receptors in the actions of extracellular uridine nucleotidesFeatures of P2X receptor-mediated synapses in the rat brain: why doesn't ATP kill the postsynaptic cell?; P2 purinoceptors in the immune system; General discussion Ill; Challenges in developing P2 purinoceptor-based therapeutics; Summing-up; Index of contributors; Subject indexMany different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions, behavioural disorders, inflammation, immunoregulation, and neuroendocrine function. This book draws together research on all aspects of P2 purinoceptors and discusses their use in different therapeutic areas.Ciba Foundation symposium ;198.PurinesReceptorsCongressesAdenosine triphosphateReceptorsCongressesNeurotransmitter receptorsCongressesPurinesReceptorsAdenosine triphosphateReceptorsNeurotransmitter receptors599599.0188612.0157Chadwick Derek91632Goode James1635507MiAaPQMiAaPQMiAaPQBOOK9910829930003321P2 purionoceptors3976328UNINA03677nam 22005655 450 991015157910332120251030105929.09781137565617113756561610.1057/978-1-137-56561-7(CKB)3710000000951899(DE-He213)978-1-137-56561-7(MiAaPQ)EBC4745453(PPN)222239964(Perlego)3500111(EXLCZ)99371000000095189920161117d2017 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierHuman Capital and Innovation Examining the Role of Globalization /edited by Sumit Kundu, Surender Munjal1st ed. 2017.London :Palgrave Macmillan UK :Imprint: Palgrave Macmillan,2017.1 online resource (XV, 254 p. 15 illus., 2 illus. in color.) Palgrave Studies in Global Human Capital Management,2662-11189781137565600 1137565608 Includes bibliographical references at the end of each chapters and index.Chapter 1: Introduction (Sumit Kundu and Surender Munjal) -- Chapter 2: Chinese innovation performance development and evolving forms of global talent flow (Paula Mckinnon) -- Chapter 3: Flexibility, Labour Utilisation and the Global Factory (Peter Enderwick) -- Chapter 4: Leading for Innovation: A balancing act (Arup Varma et al.) -- Chapter 5: Innovation in Global Human Capital Management: Disrupting the Balance between Centripetal and Centrifugal Forces (Juan I. Sanchez) -- Chapter 6: Managing Non-Traditional Human Capital in International Assignments: A Qualitative Analysis of The Talent and Innovation Gaps (Kowoon Kim and Mary Ann Glinkow) -- Chapter 7: Global virtual team as an innovative work structure (Norhayati Zakaria) -- Chapter 8: From Outsourcing to Best Sourcing: The Global Search for Talent and Innovation (Garishma Shaw) -- Chapter 9: Theorising Human Capital Formation for Innovation in India’s Global Information Technology (IT) Sector (Ashish Malik and Vijay Pereira).The second title in the Palgrave Studies in Global Human Capital Management series, this book explores how human capital contributes to innovation within the context of an inter-connected and globalized world. Investigating globalization as a phenomenon reflected within increasing cross-border flows of goods, services, know-how and talent, Human Capital and Innovation: Examining the Role of Globalization illustrates various facets of innovation at individual, team and organizational level. It highlights the influence of new economic realities, such as technological advances and the rise of emerging economies, on human capital and innovation.Palgrave Studies in Global Human Capital Management,2662-1118International economic integrationGlobalizationTechnological innovationsEmerging Markets and GlobalizationInnovation and Technology ManagementInternational economic integration.Globalization.Technological innovations.Emerging Markets and Globalization.Innovation and Technology Management.381Kundu Sumitedthttp://id.loc.gov/vocabulary/relators/edtMunjal Surenderedthttp://id.loc.gov/vocabulary/relators/edtBOOK9910151579103321Human Capital and Innovation2158898UNINA