02935nam 22005655u 450 991014880690332120211006145022.03-318-04757-0(CKB)3780000000102566(OCoLC)1046110646(SZ-BaSKA)223046(EXLCZ)99378000000010256620211006d1996 uy 0engurunu|||||Hereditary Cancer : 2nd International Research Conference on Familial Cancer, Basel, September 1995 / editors, H. Müller, R.J. Scott, W. WeberBasel : S. Karger, 19961 online resource (XII + 234 pages) : 29 figures, 37 tablesA new edition of the 'Yellow Book'!3-8055-6329-9 Molecular genetics has revolutionized our understanding of the susceptibility to and pathogenesis of cancer and is heralding the era of ‘molecular oncology’. This progress is well illustrated by the gain in knowledge accumulated since the release of ‘Familial Cancer’ in 1985 - known among experts as the ‘yellow book’. Cancer genes can now be identified, mapped and sequenced, and this technology has resulted in presymptomatic testing of persons at risk and the development of preventive therapeutic measures. This book provides an update of the latest advances by international experts in the field of hereditary cancer, with special emphasis on the needs of medical practice. The first part is devoted to a discussion of the mechanisms by which predispositions lead to breast and ovarian cancer, intestinal cancer, neoplasia of endocrine glands, and tumors in rare cancer syndromes. Attention is also given to epidemiological aspects of familial cancer occurrence. The second part covers genetic counseling and testing of members of high-risk families, as well as the prevention and treatment of hereditary cancer. Clearly written and well-organized, this book provides essential information not only for molecular geneticists and epidemiologists, but also for genetic counselors and oncologists.GeneticsOncologyCell BiologyEndocrinologyFamily PlanningGastroenterologyGynecologyMolecular BiologyPathologyGeneticsOncologyCell BiologyEndocrinologyFamily PlanningGastroenterologyGynecologyMolecular BiologyPathology616.99/4042Müller HMüller Hj(Hansjakob)355271Scott R. J319542Weber W(Walter)357539UKSKGUKSKGBOOK9910148806903321Hereditary Cancer2860988UNINA