02018nam0 2200385 i 450 SUN000570120120330110157.11388-15-07171-7IT2000 1272220020812d1999 |0itac50 baitaIT|||| |||||CostituzioneMaurizio FioravantiBolognaIl mulino[1999]184 p.21 cm.001SUN00116132001 Lessico della politica4210 BolognaIl mulino1999-.CostituzionalismoStoriaFISUNC003487Costituzioni politicheStoriaFISUNC003873BolognaSUNL000003342.0290921Fioravanti, MaurizioSUNV005051145313Il mulinoSUNV000011650ITSOL20181109RICASUN0005701UFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA00 CONS VIII.Eb.152 00 17154 UFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA00 CONS VIII.Eb.152 bis 00 26918 UFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA00 CONS VIII.Eb.157 ter 00 26917 UFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA00 CONS VIII.Eb.152 qt 00 BFG1638 UFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA17154CONS VIII.Eb.152paUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA26918CONS VIII.Eb.152 bispaUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA26917CONS VIII.Eb.157 terpaUFFICIO DI BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZABFG1638CONS VIII.Eb.152 qtpaCostituzione507132UNICAMPANIA05481nam 2200733Ia 450 991014624170332120200814014302.01-280-52085-X97866105208553-527-60597-53-527-60151-1(CKB)1000000000019329(EBL)481736(OCoLC)69156747(SSID)ssj0000148718(PQKBManifestationID)11162576(PQKBTitleCode)TC0000148718(PQKBWorkID)10225469(PQKB)10304545(MiAaPQ)EBC481736(EXLCZ)99100000000001932920030616d2003 uy 0engur|n|---|||||txtccrThe epigenome[electronic resource] molecular hide and seek /edited by S. Beck and A. OlekWeinheim ;[Cambridge] Wiley-VCHc20031 online resource (190 p.)Description based upon print version of record.3-527-30494-0 Includes bibliographical references and index.The Epigenome Molecular Hide and Seek; Preface; Contents; 1 Five Not Four: History and Significance of the Fifth Base; Summary; 1.1 Historical Introduction; 1.2 Sequencing 5-methylcytosine (5-mC) Residues in Genomic DNA; The Bisulfite Method; 1.3 Gene Silencing; 1.4 Development; 1.5 Abnormal DNA Methylation in Cancer Cells; 1.6 Nuclear Transfer; 1.7 Aging; 1.8 The Future; References; 2 (Epi)genetic Signals: Towards a Human Genome Sequence of All Five Nucleotides; Summary; 2.1 A Linguistic Prologue; 2.2 Towards the Complete Sequence of the Human Genome with Five Nucleotides2.3 Patterns of DNA Methylation - the Scaffold for Building a Functional Genome2.4 DNA Methylation Patterns in Segments of the Human Genome and in Viral Genomes; 2.4.1 On Viral Genomes and Foreign DNA Integrates (Table 2.1); 2.4.2 DNA Methylation Patterns in the Human Genome (Table 2.1); 2.5 Insertions of Foreign DNA into Established Mammalian Genomes; 2.6 De Novo Methylation of Integrated Foreign DNA; 2.6.1 Ad12 Genomes in Hamster Tumor Cells; 2.6.2 De Novo Methylation of Foreign DNA Integrated into the Mouse Genome by Homologous or Heterologous Recombination [23]2.7 Genome-wide Perturbations in the Mammalian Genome upon Foreign DNA Insertion2.8 Outlook and Recommendations; References; 3 Epi Meets Genomics: Technologies for Finding and Reading the 5(th) Base; Summary; 3.1 The Development of 5(th)-Base Technologies; 3.1.1 Unusual DNA-cutting Enzymes; 3.1.2 A Unique Chemical Reaction that Modifies Methylated DNA; 3.1.3 The Advance of 5(th) Base Technologies in Epigenomic Research; 3.2 Restriction Landmark Genomic Scanning (RLGS): Finding the 5(th)-base Signposts in the Genomic Atlas; 3.2.1 Principle; 3.2.2 How Does RLGS Work?; 3.2.3 Applications3.3 Methylation-sensitive Arbitrarily Primed (AP) PCR: Fishing for the 5(th) Bases in Genomic Ponds3.3.1 Principle; 3.3.2 How Does MS AP-PCR Work?; 3.3.3 Applications; 3.4 Differential Methylation Hybridization (DMH): Identifying the 5(th) Bases in the Genomic Crossword Puzzle; 3.4.1 Principle; 3.4.2 How Does DMH Work?; 3.4.3 Applications; 3.5 MethyLight: Finding 5(th)-base Patterns in Genomic Shadows; 3.5.1 Principle; 3.5.2 How Does MethyLight Work?; 3.5.3 Applications; 3.6 Exploring the Epigenome; References; 4 Mammalian Epigenomics: Reprogramming the Genome for Development and TherapySummary4.1 Introduction; 4.2 DNA Methylation; 4.3 Histone Modifications; 4.4 Imprinting; 4.5 Reprogramming and Cloning; 4.6 Epimutations and Epigenetic Inheritance; 4.7 Epigenomics: The Future; 4.7 Conclusions; References; 5 At the Controls: Genomic Imprinting and the Epigenetic Regulation of Gene Expression; Summary; 5.1 Introduction; 5.2 Genomic Imprinting; 5.2.1 The Role of DNA Methylation in Imprinted Gene Expression; 5.2.3 Organization of Imprinted Genes5.2.4 The Mechanism of Imprinting at the Mouse Igf2r Imprinted Domain Requires a Cis-acting Noncoding Antisense Transcript Regulated by DNA Methylation (Fig. 5.2 a)This is the first book that describes the role of the Epigenome (cytosine methylation) in the interplay between nature and nurture. It focuses and stimulates interest in what will be one of the most exciting areas of post-sequencing genome science: the relationship between genetics and the environment. Written by the most reputable authors in the field, this book is essential reading for researchers interested in the science arising from the human genome sequence and its implications on health care, industry and society.Human genomeMedical geneticsNature and nurtureGenome, HumanGenomicsmethodsCytosinephysiologyElectronic books.Human genome.Medical genetics.Nature and nurture.Genome, Human.Genomicsmethods.Cytosinephysiology.599.935611.01816Olek A(Alexander)877325Beck Stephan(Stephan G.)877326MiAaPQMiAaPQMiAaPQBOOK9910146241703321The epigenome1959092UNINA