04425nam 2200649Ia 450 991014544020332120180612233952.01-281-06941-897866110694140-470-69232-40-470-76651-4(CKB)1000000000402079(EBL)320087(OCoLC)476116586(SSID)ssj0000176875(PQKBManifestationID)11182948(PQKBTitleCode)TC0000176875(PQKBWorkID)10210099(PQKB)10256053(MiAaPQ)EBC320087(EXLCZ)99100000000040207920070829d2007 uy 0engur|n|---|||||txtccrImmune dysfunction and immunotherapy in heart disease[electronic resource] /edited by Ronald Ross Watson & Douglas F. LarsonOxford Blackwell20071 online resource (323 p.)Description based upon print version of record.1-4051-5568-X Includes bibliographical references and index.Immune Dysfunction and Immunotherapy in Heart Disease; Contents; Contributors; Preface; About the Editors; Part I Immune dysfunction leading to heart disease: induction by physiological changes; 1 Immunosuppression by ultraviolet light-B radiation: a mediator of cardiac remodeling; 2 Immune mechanisms in pediatric cardiovascular disease; 3 Heart failure-role of autoimmunity; 4 Immune basis of hypertension in humans; 5 Immune dysregulation: potential mediator metabolic syndrome-induced cardiac remodeling; 6 T helper 2 cell cytokines in remodeling of aortic wall7 Effects of TNF-a on cardiac function8 Immunosuppression in promotion of cardiac allograft vasculopathy; 9 Immunotherapy for left ventricular dysfunction after heart transplantation; Part II Immune dysfunction promoting CVD: induction by transplantation drugs; 10 Immunomodulating therapy in chronic heart failure; 11 Statins in atherosclerosis: role of immune regulation; 12 ACE inhibitors as immunomodulators: treatment of cardiovascular disease; 13 Treatment of heart failure by anticytokine therapiesPart III Immune dysfunction leading to heart dysfunction: induction or prevention by cardiotherapeutic drugs14 Pathogenesis of cardiovascular complications in the acquired immunodeficiency syndrome; 15 Cytokines and T cell-mediated responses in autoimmune myocarditis; 16 Drugs of abuse: accentuation of immunomodulation of viral myocarditis; Part IV Immune dysfunction leading to heart disease: induction by pathogens; 17 Osteopontin: the link between the immune system and cardiac remodeling; 18 Inflammatory immune activation in heart failure patients: therapeutic implications26 Role of oral pathogens in the pathogenesis of coronary heart disease27 Myocardial regenerative potential by stem cell transplant; 28 Bioflavanoids and dietary anti-inflammatory actions: role in cardiovascular diseases; IndexCurrent heart failure therapeutics affects symptoms without appreciably reducing the mortality rate of 50% in five years -- suggesting a failure in treating the underlying mechanism. This book proposes a new mechanism for heart failure; immune mediated cardiac remodelling for cardiac dysfunction. The outstanding editor team of two internationally recognized immunologists -- Ronald Watson, who has studied heart disease in immune dysfunction for a decade and has a patent for an immunotherapy of heart disease by immune regulation, and Douglas Larson, whose experience in cardiac transplantatHeartDiseasesImmunological aspectsHeartDiseasesImmunotherapyImmunologic diseasesComplicationsElectronic books.HeartDiseasesImmunological aspects.HeartDiseasesImmunotherapy.Immunologic diseasesComplications.616.1/207616.1207YB 9022rvkWatson Ronald R(Ronald Ross)872276Larson Douglas F941282MiAaPQMiAaPQMiAaPQBOOK9910145440203321Immune dysfunction and immunotherapy in heart disease2123134UNINA