04610nam 2200673Ia 450 991014529140332120230828214450.01-281-32201-697866113220140-470-75061-80-470-75022-7(CKB)1000000000403880(EBL)351017(OCoLC)437214022(SSID)ssj0000123721(PQKBManifestationID)11159782(PQKBTitleCode)TC0000123721(PQKBWorkID)10011112(PQKB)10632791(MiAaPQ)EBC351017(Au-PeEL)EBL351017(CaPaEBR)ebr10232989(CaONFJC)MIL132201(EXLCZ)99100000000040388020051129d2006 uy 0engur|n|---|||||txtccrClinical trials explained[electronic resource] a guide to clinical trials in the NHS for healthcare professionals /editors, Derek Stewart ... et al. ; produced by the British Medical Journal (BMJ), in association with the National Translational Cancer Research Network (NTRAC) and Emergency Care Research Institute (ECRI)Malden, MA Blackwell Pub.c20061 online resource (114 p.)Description based upon print version of record.0-7279-1858-3 Includes bibliographical references and index.Clinical Trials Explained: A Guide to Clinical Trials in the NHS for Healthcare Professionals; Contents; Preface; Acknowledgements; Chapter 1 Overview and Purpose of this Guide to Clinical Trials in the NHS; Overview and purpose of this guide; Who should use this guide to clinical trials in the NHS?; Chapter 2 Clinical Trials Explained; What are clinical trials?; Why are clinical trials needed?; Who is involved in a clinical trial?; How are clinical trials designed and approved?; Progression of a medical intervention through the clinical trial phases; SummaryChapter 3 Clinical Trial Approval, Regulation and FundingHow are clinical trials approved and regulated?; Ethical approval; Informed consent; How are trials managed?; Who pays for a clinical trial?; Summary; Chapter 4 Understanding Clinical Trial Design and Results; Understanding randomisation and blinding in clinical trials; Understanding controls and placebos; Why are placebos used in clinical trials?; What about trials that are not controlled or blinded?; Understanding clinical trial results; Summary; Chapter 5 Questions About Clinical Trials: A Framework for DiscussionWhat are patients' rights?Why do patients take part in clinical trials?; Why do patients decline to take part in a clinical trial or withdraw from a clinical trial they are involved in?; How can patients be empowered during their involvement in a clinical trial?; Will patients involved in clinical trials need extra help and support from their carers?; What are the likely costs of and reimbursement for patients participating in clinical trials?; Summary; Appendix A Finding Out About Clinical Trials that are Currently or Soon to be RecruitingAppendix B ECRI Evidence Report: Patients' Reasons for Participation in Clinical Trials and Effect of Trial Participation on Patient OutcomesGlossary; IndexWhat will happen during and after a clinical trial?How will a trial affect my quality of life?What are the benefits and risks of a trial?What does giving consent mean and what will it involve?Will I incur costs during and because of the trial? These are the questions that should be raised every time a health care professional talks through with a patient the pros and cons of entering a clinical trial. Clinical Trials Explained has been designed in consultation with doctors and patients who have taken part in trials, providing an essential and detailed guClinical trialsGreat BritainClinical trialsDecision makingNational health servicesGreat BritainClinical trialsClinical trialsDecision making.National health services610.72/4615.50724Stewart Derek1951-939840National Translational Cancer Research Network.Emergency Care Research Institute.MiAaPQMiAaPQMiAaPQBOOK9910145291403321Clinical trials explained2119014UNINA