03240nam 2200649Ia 450 991014474720332120170816121634.01-282-34758-697866123475800-470-51373-X0-470-51374-8(CKB)1000000000377200(EBL)470392(SSID)ssj0000303137(PQKBManifestationID)11265537(PQKBTitleCode)TC0000303137(PQKBWorkID)10274585(PQKB)11581201(MiAaPQ)EBC470392(OCoLC)181170884(EXLCZ)99100000000037720019890425d1988 uy 0engur|n|---|||||txtccrMetastasis[electronic resource]Chichester, UK ;New York Wiley19881 online resource (268 p.)Ciba Foundation symposium ;141"Symposium on Metastasis, held at the Ciba Foundation, London, 19-21 April 1988. Editors: Gregory Bock (organizer) and Julie Whelan" --P."A Wiley-Interscience publication."0-471-91513-0 Includes bibliographies and indexes.METASTASIS; Contents; Participants; Introduction; Tissue organizational stability and intercelIular invasion; Functional role of specific secreted and cell surface molecules in tumour cell invasion and metastasis; Adhesion mechanisms in embryogenesis and in cancer invasion and metastasis; The cell interaction sites of fibronectin in tumour metastasis; Oncogene induction of metastases; Adhesive properties of metastasizing tumour cells; Clonal changes in tumours during growth and progression evaluated by Southern gel analysis of random integrations of foreign DNAMolecuIar genetics of metastasisThe reversal of the metastatic phenotype by gene transfer; Inhibitors of collagenase IV and cell adhesion reduce the invasive activity of malignant tumour cells; Macrophage therapy of cancer metastasis; Clinical aspects of metastases; Index of contributors; Subject indexAn international group of researchers addresses basic mechanism involved in the metastatic spread of tumors and considers new methods of prevention and treatment. Compares behavior of normal and abnormal cells, with emphasis on cell surface mechanisms--especially invasive processes--and inhibitors that might prevent metastasis. Also discusses determination of the metastatic genotype, the role of the immune system, and reduction of metastasis via liposome-activated macrophages.Ciba Foundation symposium ;141.MetastasisCongressesInternal medicineElectronic books.MetastasisInternal medicine.591.2616.99616.992071Bock Gregory322650Whelan Julie322651Symposium on Metastasis(1988 :Ciba Foundation)MiAaPQMiAaPQMiAaPQBOOK9910144747203321Metastasis2134414UNINA