03741nam 2200673 a 450 991014466430332120230213211634.01-280-78418-097866136945770-470-72097-20-470-71867-6(CKB)1000000000688055(EBL)703936(OCoLC)797918543(SSID)ssj0000715056(PQKBManifestationID)11394642(PQKBTitleCode)TC0000715056(PQKBWorkID)10678041(PQKB)11131529(MiAaPQ)EBC703936(Au-PeEL)EBL703936(CaPaEBR)ebr10575528(CaONFJC)MIL369457(EXLCZ)99100000000068805519880825d1985 uy 0engur|n|---|||||txtccrGrowth factors in biology and medicine[electronic resource] /[editors, David Evered, Jonathan Nugent, and Julie Whelan.]London Pitman Pub.19851 online resource (296 p.)Ciba Foundation symposium ;116"Symposium on Growth Factors in Biology and Medicine, held at the Ciba Foundation, London, 22-24 January, 1985"--Contents page.0-470-66444-4 0-272-79818-5 Includes bibliographical references and indexes.Growth factors in biology and medicine; Contents; Introduction; Growth factors in mammalian embryogen-esis; Discussion; The EGF receptor kinase: evidence for allos- teric activation and intramolecular self-phosphorylation; Discussion; Role of growth factors in oncogenesis: growth factor-proto-oncogene pathways of mitogenesis; Discussion; Signalling mitogene- sis in 3T3 cells: role of Ca*+-sensitive, phospholipid-dependent protein kinase; Discussion; The PDGF-inducible 'compe- tence genes': intracellular mediators of the mitogenic response; DiscussionPlatelet-derived growth factor: its potential roles in wound-healing, atherosclerosis, neoplasia, and growth and developmentDiscussion; Nerve growth factor; Discussion; The role of haemopoietic cell growth factor (interleukin 3) in the development of haemopoietic cells; Discussion; Haemopoietic growth factors: structure and receptor interac- tions; Discussion; In vivo effects of the insulin-like growth factors (IGFs) in the hypophysectomized rat: comparison with human growth hormone and the possible role of the specific IGF carrier proteins; DiscussionProtein phosphorylation and growth controlDiscussion; Receptors for the phorbol ester tumour promoters; Discussion; Ectopic peptides released by a human mela- noma cell line that modulate the transformed phenotype; Discussion; A growth regula- tory factor that can both inhibit and stimulate growth; Discussion; Final general discussion Receptor modulation and signalling systems; Biological functions of growth factors; Medical aspects of growth factors; Index of contributors; Subject indexCiba Foundation symposium ;116.Growth factorsPhysiological effectCongressesCell proliferationCongressesCellsGrowthRegulationCongressesGrowth factorsPhysiological effectCell proliferationCellsGrowthRegulation612/.6Evered David857127Nugent Jonathan845868Whelan Julie322651MiAaPQMiAaPQMiAaPQBOOK9910144664303321Growth factors in biology and medicine2117305UNINA