04425nam 2200685 a 450 991014465490332120230213211704.01-280-78402-497866136944160-470-72076-X0-470-71846-3(CKB)1000000000688149(EBL)703915(OCoLC)797918499(SSID)ssj0000715494(PQKBManifestationID)11400817(PQKBTitleCode)TC0000715494(PQKBWorkID)10703767(PQKB)10330227(MiAaPQ)EBC703915(Au-PeEL)EBL703915(CaPaEBR)ebr10575609(CaONFJC)MIL369441(EXLCZ)99100000000068814919830426d1983 uy 0engurcn|||||||||txtccrBrush border membranes[electronic resource]London Pitmanc19831 online resource (352 p.)Ciba Foundation symposium ;v. 95Editors: Ruth Porter (Organizer) and Geralyn M. Collins.Proceedings of Symposium on: Brush border membranes held at the Ciba Foundation, London, 8-10 June 1982.0-470-66413-4 0-272-79659-X Includes bibliographical references and indexes.Brush border membranes; Contents; Chairman's introduction; Introductory remarks on the brush border; Microvillar endopeptidase, an enzyme with special topological features and a wide distribution; Discussion; Aminopeptidases and proteolipids of intestinal brush border; Discussion; Structure of microvillar enzymes in different phases of their life cycles; Discussion; Specific labelling of the hydrophobic domain of rat renal y-glutamyl transferase; Discussion; Biosynthesis and assembly of the largest and major intrinsic polypeptide of the small intestinal brush borders; DiscussionUse of monoclonal antibodies in the study of intestinal structure and function Discussion; Biosynthesis and transport of plasma membrane glyco- proteins in the rat intestinal epithelial cell: studies with sucrase- isomaltase; Discussion; GENERAL DISCUSSION I Biosynthesis and assembly of brush border proteins: (i) some co-translational models for protein insertion into membranes; molecular sizes of brush border enzymes during assembly; Distribution of enteropeptidase and aminopeptidase to non-brush border sites; General functions of the enterocyteMolecular architecture of the microvillus cytoskeleton Discussion; Structure of human placental microvilli; Discussion; Regulation of cytoskeletal structure and contractility in the brush border; Discussion; Characterization of membrane glycoproteins involved in attachment of microfilaments to the microvillar membrane; Discussion; Structural and functional relationship between the membrane and the cytoskeleton in brush border microvilli; Discussion; GENERAL DISCUSSION II A pathological condition due to congenital disorganization of the brush borderConformational changes in the a-subunit, and cation transport by Na+, K+-ATPase Discussion; Properties of immunoglobulin G-Fc receptors from neonatal rat intestinal brush borders; Immunoglobulin G receptors of intestinal brush borders from neonatal rats; Discussion after the preceding two papers; Cotransport systems in the brush border membrane of the human placenta; Discussion; GENERAL DISCUSSION III Cytoskeleton and membrane-cytoskeleton interactions; The importance of structure for understanding the biosynthetic process; Future advances in study of brush border cytoskeletonPhoto-affinity labeling to identify components of the neutral amino acid carrier in the intestinal microvillar membrane Chairman's closing remarks; Index to contributors; Subject indexCiba Foundation symposium ;v. 95.Cell membranesCongressesCell physiologyCongressesCell membranesCell physiology611.0181611/.0181Porter Ruth64811Collins Geralyn M868426MiAaPQMiAaPQMiAaPQBOOK9910144654903321Brush border membranes1991734UNINA