03438nam 2200637Ia 450 991014456030332120170816122143.01-282-34788-897866123478870-470-51455-80-470-51456-6(CKB)1000000000377137(EBL)470550(OCoLC)609849502(SSID)ssj0000304156(PQKBManifestationID)11229498(PQKBTitleCode)TC0000304156(PQKBWorkID)10277867(PQKB)11746553(MiAaPQ)EBC470550(EXLCZ)99100000000037713719930831d1994 uy 0engur|n|---|||||txtccrNeural tube defects[electronic resource] /[editors, Gregory Bock and Joan Marsh]Chichester ;New York Wiley19941 online resource (312 p.)Ciba Foundation symposium ;181"Symposium on Neural Tube Defects held at the Ciba Foundation, London, 18-20 May 1993"--Contents p.v.0-471-94172-7 Includes bibliographical references and index.NEURAL TUBE DEFECTS; Contents; Participants; Introduction; Normal neurulation in amphibians; Formation and patterning of the avian neuraxis: one dozen hypotheses; Normal neurulation in mammals; Neurulation in the normal human embryo; Molecular genetics of neurulation; Pax genes and neural tube defects in the mouse; Genetic models of mammalian neural tube defects; Valproic acid-induced neural tube defects; Vitamins, folic acid and the cause and prevention of neural tube defects; Folic acid metabolism and mechanisms of neural tube defectsFolic acid and neural tube defects: the current evidence and implications for preventionPrevention of folic acid-preventable spina bifida and anencephaly; Spina bifida: anticonvulsants and other maternal influences; General discussion; Screening for neural tube defects; Meningomyelocele: management in utero and post natum; Final discussion; Index of contributors; Subject indexNeural tube defects are the second most common cause of perinatal death from birth defects in the United Kingdom. In this important book, leading scientists evaluate the latest evidence on the causative factors--both genetic and environmental--of these major human congenital malformations. They also discuss prospects for early detection by prenatal screening and for treatment both before and after birth. The extensive coverage encompasses such topics as: formation and patterning of the avian neuraxis, neurulation in mammals and the normal human embryo, folic acid and more.Ciba Foundation symposium ;181.Neural tubeAbnormalitiesCongressesNervous systemAbnormalitiesCongressesElectronic books.Neural tubeAbnormalitiesNervous systemAbnormalities612.6612.64018616.8Bock Gregory322650Marsh Joan91633Symposium on Neural Tube Defects(1993 :Ciba Foundation)MiAaPQMiAaPQMiAaPQBOOK9910144560303321Neural tube defects2105828UNINA