04755nam 2200649 450 991014440690332120190715152939.01-282-02171-097866120217183-527-62521-63-527-62522-4(CKB)1000000000577977(EBL)482075(OCoLC)609855520(SSID)ssj0000298178(PQKBManifestationID)11223412(PQKBTitleCode)TC0000298178(PQKBWorkID)10361737(PQKB)10431107(MiAaPQ)EBC482075(PPN)15233999X(EXLCZ)99100000000057797720160815h20092009 uy 0engur|n|---|||||txtccrHandbook of GC/MS fundamentals and applications /Hans-Joachim Hübschmann2nd ed.Weinheim, [Germany] :Wiley-VCH Verlag GmbH & Co. KGaA,2009.©20091 online resource (739 p.)Description based upon print version of record.3-527-31427-X Includes bibliographical references at the end of each chapters and index.Handbook of GC/MS; Foreword; Preface to the Second Edition; Preface to the First Edition; Contents; 1 Introduction; 2 Fundamentals; 2.1 Sample Preparation; 2.1.1 Solid Phase Extraction; 2.1.1.1 Solid Phase Microextraction; 2.1.2 Supercritical Fluid Extraction; 2.1.3 Pressurized Fluid Extraction; 2.1.4 Online Liquid Chromatography Clean-up; 2.1.5 Headspace Techniques; 2.1.5.1 Static Headspace Technique; 2.1.5.2 Dynamic Headspace Technique (Purge and Trap); 2.1.5.3 Headspace versus Purge and Trap; 2.1.6 Adsorptive Enrichment and Thermodesorption; 2.1.6.1 Sample Collection; 2.1.6.2 Calibration2.2.3.4 Cold Injection Systems2.2.3.5 Injection Volumes; 2.2.3.6 On-column Injection; 2.2.3.7 Cryofocusing; 2.2.4 Capillary Columns; 2.2.4.1 Sample Capacity; 2.2.4.2 Internal Diameter; 2.2.4.3 Film Thickness; 2.2.4.4 Column Length; 2.2.4.5 Adjusting the Carrier Gas Flow; 2.2.4.6 Properties of Stationary Phases; 2.2.5 Chromatography Parameters; 2.2.5.1 The Chromatogram and its Meaning; 2.2.5.2 Capacity Factor k ́; 2.2.5.3 Chromatographic Resolution; 2.2.5.4 Factors Affecting the Resolution; 2.2.5.5 Maximum Sample Capacity; 2.2.5.6 Peak Symmetry; 2.2.5.7 Optimisation of Flow2.2.6 Classical Detectors for GC/MS Systems2.2.6.1 FID; 2.2.6.2 NPD; 2.2.6.3 ECD; 2.2.6.4 PID; 2.2.6.5 ELCD; 2.2.6.6 FPD; 2.2.6.7 PDD; 2.2.6.8 Connection of Classical Detectors Parallel to the Mass Spectrometer; 2.3 Mass Spectrometry; 2.3.1 Resolving Power and Resolution in Mass Spectrometry; 2.3.1.1 High Resolution; 2.3.1.2 Unit Mass Resolution; 2.3.1.3 High and Low Resolution in the Case of Dioxin Analysis; 2.3.2 Time-of-Flight Analyser; 2.3.3 Isotope Ratio Monitoring GC/MS; 2.3.4 Ionisation Procedures; 2.3.4.1 Electron Impact Ionisation; 2.3.4.2 Chemical Ionisation2.3.5 Measuring Techniques in GC/MS2.3.5.1 Detection of the Complete Spectrum (Full Scan); 2.3.5.2 Recording Individual Masses (SIM/MID); 2.3.5.3 High Resolution Accurate Mass MID Data Acquisition; 2.3.6 MS/MS -Tandem Mass Spectrometry; 2.3.7 Mass Calibration; 2.4 Special Aspects of GC/MS Coupling; 2.4.1 Vacuum Systems; 2.4.2 GC/MS Interface Solutions; 2.4.2.1 Open Split Coupling; 2.4.2.2 Direct Coupling; 2.4.2.3 Separator Techniques; References for Chapter 2; 3 Evaluation of GC/MS Analyses; 3.1 Display of Chromatograms; 3.1.1 Total Ion Current Chromatograms; 3.1.2 Mass Chromatograms3.2 Substance IdentificationThis is the first comprehensive reference work for GC/MS now in its second edition.It offers broad coverage, from sample preparation to the evaluation of MS-Data, including library searches. Fundamentals, techniques, and applications are described.A large part of the book is devoted to numerous examples for GC/MS-applications in environmental, food, pharmaceutical and clinical analysis. These proven examples come from the daily practice of various laboratories.The book also features a glossary of terms and a substance index that helps the reader to find information for his particulGas chromatographyMass spectrometryGas chromatography.Mass spectrometry.543.85543/.85Hübschmann Hans-Joachim724432Wiley Online Library (Servicio en línea)MiAaPQMiAaPQMiAaPQBOOK9910144406903321Handbook of GC1419266UNINA