03474nam 2200625 a 450 991014429790332120221215202909.01-282-12236-397866121223610-470-51384-50-470-51385-3(CKB)1000000000376480(EBL)470477(OCoLC)609849394(SSID)ssj0000364333(PQKBManifestationID)11262318(PQKBTitleCode)TC0000364333(PQKBWorkID)10394615(PQKB)11263345(MiAaPQ)EBC470477(EXLCZ)99100000000037648019890710d1989 uy 0engur|n|---|||||txtccrPhotosensitizing compounds[electronic resource] their chemistry, biology and clinical useChichester ;New York Wiley19891 online resource (252 p.)Ciba Foundation symposium ;146"A Wiley-Interscience publication."0-471-92308-7 Includes bibliographical references and indexes.PHOTOSENSITIZING COMPOUNDS: THEIR CHEMISTRY, BIOLOGY AND CLINICAL USE; Contents; Introduction; What are the ideal photoproperties for a sensitizer?; The chemistry, photophysics and photosensitizing properties of phthalocyanines; General discussion : Comparison of haematoporphyrin derivative and new photosensitizers; Porphyrins as photosensitizers; Photodynamic therapy: light delivery and dosage for second-generation photosensitizers; In vivo transport and pharmacokinetic behaviour of tumour photosensitizers; Intracellular localization of photosensitizersTissue localization of photosensitizers and the mechanism of photodynamic tissue destructionImmunosuppression in phototherapy; Effects of porphyrins on skin; Photosensitizing compounds in the treatment of psoriasis; Extracorporeal photochemotherapy in the treatment of cutaneous T cell lymphoma and autoimmune disorders affecting the skin; Photodynamic therapy of early-stage lung cancer; Long-term experience with integral photodynamic therapy of TIS bladder carcinoma; Photoradiation therapy of brain tumours; Final general discussion : Drug and light doses for photodynamic therapyChairman's summing-upIndex of contributors; Subject indexCertain organic compounds can become toxic to biological tissue when activated by light. Many medical applications of this effect have been studied over the past twenty years, and This symposium brings together chemists, biologists, and clinicians to discuss the basic chemistry of the sensitizing compounds, their biological effects, and clinical applications in treatments of various cancers and skin disorders.Ciba Foundation symposium ;146.Photosensitizing compoundsTherapeutic useTestingCongressesPhotosensitizing compoundsCongressesCancerPhotochemotherapyCongressesPhotosensitizing compoundsTherapeutic useTestingPhotosensitizing compoundsCancerPhotochemotherapy540615.8615.831MiAaPQMiAaPQMiAaPQBOOK9910144297903321Photosensitizing compounds2274168UNINA