02536nam 22006014a 450 991014411840332120170810183318.01-281-81450-497866118145020-470-37061-00-470-36916-7(CKB)1000000000549398(EBL)362144(OCoLC)264714700(SSID)ssj0000141603(PQKBManifestationID)11136183(PQKBTitleCode)TC0000141603(PQKBWorkID)10058463(PQKB)11515335(MiAaPQ)EBC362144(PPN)198275242(EXLCZ)99100000000054939820071209d2008 uy 0engur|n|---|||||txtccrDrug-DNA interactions[electronic resource] structures and spectra /Kazuo Nakamoto, Masamichi Tsuboi, Gary D. StrahanHoboken, N.J. John Wiley & Sonsc20081 online resource (396 p.)Description based upon print version of record.0-471-78626-8 Includes bibliographical references and index.DNA structures and spectra -- Intercalating drugs -- Groove-binding drugs -- Covalent bonding drugs -- Strand-breaking drugs -- Metal-containing drugs.Learn vital information about drug-DNA interactions from Drug-DNA Interactions: Structures and Spectra, the only comprehensive book written about this topic. Understand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. Find detailed information about X-ray crystallography, NMR spectroscopy, molecular modeling, and optical spectroscopy such as UV-Visible absorption, fluorescence, circular dichroism (CD), flow linear dDNA-drug interactionsResearchMethodologyDNASpectraDrugsSpectraDNA-drug interactionsResearchMethodology.DNASpectra.DrugsSpectra.572.8/6Nakamoto Kazuo1922-23085Tsuboi Masamichi1925-92535Strahan Gary D928917MiAaPQMiAaPQMiAaPQBOOK9910144118403321Drug-DNA interactions2087723UNINA