02994nam 22005534a 450 991014411390332120230721033054.01-281-93903-X97866119390380-470-42246-70-470-42245-9(CKB)1000000000549814(EBL)380571(OCoLC)437241507(SSID)ssj0000131475(PQKBManifestationID)11134966(PQKBTitleCode)TC0000131475(PQKBWorkID)10026072(PQKB)11497513(MiAaPQ)EBC380571(Au-PeEL)EBL380571(CaPaEBR)ebr10263634(CaONFJC)MIL193903(EXLCZ)99100000000054981420081021d2009 uy 0engur|n|---|||||txtccrCoupled bioluminescent assays[electronic resource] methods, evaluations, and applications /Michael J. CoreyHoboken, N.J. Wileyc20091 online resource (326 p.)Description based upon print version of record.0-470-10883-5 Includes bibliographical references (p. 265-289) and index.Introduction -- Coupled bioluminescent reactions in practice -- Coupled bioluminescent cytotoxicity assays -- The role of coupled bioluminescent assays in kinase screening and study -- Coupled bioluminescent phosphatase assays -- Acetylcholinesterase -- Measurement of nitric oxide synthase activity by coupled bioluminescence -- The coupled bioluminescent pyrophosphorolysis assay -- Coupled luminescent assays of G-protein-coupled receptors -- Coupled bioluminescent protease assays -- Coupled luminescent assays involving aequorin -- Coupled bioluminescent reporter assays -- Coupled bioluminescent assays : regulatory concerns -- Coupled bioluminescent determination of bioburden and sterility -- Environmental applications of coupled bioluminescent assays.This book highlights the applications of coupled bioluminescence assay techniques to real-world problems in drug discovery, environmental and chemical analysis, and biodefense. It separates theoretical aspects from the applied sections in a clear and readable way. Coupled Bioluminescent Assays, explains the uses of CB technologies across drug discovery to analyze toxicity, drug receptors, and enzymes. It covers applications in environmental analysis and biodefense, including cytotoxicity, fertilizer and explosives analysis, and nerve agent and pesticide detection. This is the premier referenceBioluminescence assayBioluminescence assay.612/.01442Corey Michael J(Michael James),1953-989967MiAaPQMiAaPQMiAaPQBOOK9910144113903321Coupled bioluminescent assays2264268UNINA