03342nam 2200601 a 450 991014401210332120170816122311.01-282-34782-997866123478250-470-51434-50-470-51435-3(CKB)1000000000376016(EBL)470503(OCoLC)609849437(SSID)ssj0000309089(PQKBManifestationID)11235253(PQKBTitleCode)TC0000309089(PQKBWorkID)10259694(PQKB)10573638(MiAaPQ)EBC470503(EXLCZ)99100000000037601619920727d1992 uy 0engur|n|---|||||txtccrSecondary metabolites[electronic resource] their function and evolution /[editors, Derek J. Chadwick and Julie Whelan]Chichester [England] ;New York Wiley19921 online resource (330 p.)Ciba Foundation symposium ;171"A Wiley-Interscience publication."0-471-93447-X Includes bibliographical references and indexes.SECONDARY METABOLITES: THEIR FUNCTION AND EVOLUTION; Contents; Introduction; Microbial secondary metabolism: a new theoretical frontier for academia, a new opportunity for industry; Evolution of secondary metabolite production: potential roles for antibiotics as prebiotic effectors of catalytic RNA reactions; Why are secondary metabolites synthesized? Sophistication in the inhibition of cell wall biosynthesis by vancomycin group antibiotics; Origins of secondary metabolism; Genes for polyketide secondary metabolic pathways in microorganisms and plantsGenes for the biosynthesis of B-lactam compounds in microorganismsRegulation of gibberellin formation by the fungus Gibberella fujikuroi; Genetic regulation of secondary metabolic pathways in Streptomyces; Terpenoid cyclases: design and function of electrophilic catalysts; Role of secondary metabolites from microbes; Self-protection mechanisms in antibiotic producers; Useful functions of microbial metabolites; Secondary metabolites from marine organisms; Roles for secondary metabolites in plants; Defensins: endogenous antibiotic peptides from human leukocytesFinal discussion: Metabolism and cell individualizationOrigins of secondary metabolism; Index of contributors; Subject indexA comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms. Examines the traditional context of secondary metabolites as natural products having no obvious part to play in the producing organism's life cycle. Covers issues related to genetic and antibiotic applications.Ciba Foundation symposium ;171.Metabolism, SecondaryCongressesElectronic books.Metabolism, Secondary574.19574.1924Chadwick Derek91632Whelan Julie322651MiAaPQMiAaPQMiAaPQBOOK9910144012103321Secondary metabolites2041674UNINA