03994nam 22006254a 450 991014358150332120170815111550.01-280-72226-697866107222660-470-05042-X0-470-05041-1(CKB)1000000000355152(EBL)281567(OCoLC)163815707(SSID)ssj0000227389(PQKBManifestationID)11200553(PQKBTitleCode)TC0000227389(PQKBWorkID)10264794(PQKB)11737042(MiAaPQ)EBC281567(EXLCZ)99100000000035515220060314d2006 uy 0engur|n|---|||||txtccrPrinciples of mass spectrometry applied to biomolecules[electronic resource] /edited by Julia Laskin, Chava LifshitzHoboken, N.J. Wiley-Intersciencec20061 online resource (707 p.)Wiley-Interscience series in mass spectrometryDescription based upon print version of record.0-471-72184-0 Includes bibliographical references and index.PRINCIPLES OF MASS SPECTROMETRY APPLIED TO BIOMOLECULES; CONTENTS; CONTRIBUTORS; PREFACE; PART I STRUCTURES AND DYNAMICS OF GAS-PHASE BIOMOLECULES; 1 Spectroscopy of Neutral Peptides in the Gas Phase: Structure, Reactivity, Microsolvation, Molecular Recognition; 2 Probing the Electronic Structure of Fe-S Clusters: Ubiquitous Electron Transfer Centers in Metalloproteins Using Anion Photoelectron Spectroscopy in the Gas Phase; 3 Ion-Molecule Reactions and H/D Exchange for Structural Characterization of Biomolecules4 Understanding Protein Interactions and Their Representation in the Gas Phase of the Mass Spectrometer5 Protein Structure and Folding in the Gas Phase: Ubiquitin and Cytochrome c; 6 Dynamical Simulations of Photoionization of Small Biological Molecules; 7 Intramolecular Vibrational Energy Redistribution and Ergodicity of Biomolecular Dissociation; PART II ACTIVATION, DISSOCIATION, AND REACTIVITY; 8 Peptide Fragmentation Overview; 9 Peptide Radical Cations; 10 Photodissociation of Biomolecule Ions: Progress, Possibilities, and Perspectives Coming from Small-Ion Models11 Chemical Dynamics Simulations of Energy Transfer and Unimolecular Decomposition in Collision-Induced Dissociation (CID) and Surface-Induced Dissociation (SID)12 Ion Soft Landing: Instrumentation, Phenomena, and Applications; 13 Electron Capture Dissociation and Other Ion-Electron Fragmentation Reactions; 14 Biomolecule Ion-Ion Reactions; PART III THERMOCHEMISTRY AND ENERGETICS; 15 Thermochemistry Studies of Biomolecules; 16 Energy and Entropy Effects in Gas-Phase Dissociation of Peptides and Proteins; INDEXAn extensive compilation of articles by leading professionals, this reference explains the fundamental principles of mass spectrometry as they relate to the life sciences. Topics covered include spectroscopy, energetics and mechanisms of peptide fragmentation, electron capture dissociation, ion-ion and ion-molecule reactions, reaction dynamics, collisional activation, soft-landing, protein structure and interactions, thermochemistry, and more. The book empowers readers to develop new ways of using these techniques.Wiley-Interscience series on mass spectrometry.Mass spectrometryBiomoleculesAnalysisElectronic books.Mass spectrometry.BiomoleculesAnalysis.543.65543/.65Laskin Julia1967-1000590Lifshitz Chava1000591MiAaPQMiAaPQMiAaPQBOOK9910143581503321Principles of mass spectrometry applied to biomolecules2296611UNINA