03975nam 2200637Ia 450 991014347960332120170809170640.01-280-26907-397866102690750-470-09082-00-470-09083-9(CKB)111090529060254(EBL)189446(OCoLC)437056972(SSID)ssj0000204825(PQKBManifestationID)11200636(PQKBTitleCode)TC0000204825(PQKBWorkID)10188722(PQKB)11417548(MiAaPQ)EBC189446(EXLCZ)9911109052906025420030723d2003 uy 0engur|n|---|||||txtccrMolecular clocks and light signalling[electronic resource] /[editors, Derek J. Chadwick and Jamie A. Goode]Chichester, UK ;Hoboken, NJ Wiley20031 online resource (308 p.)Novartis Foundation symposium ;253"Held at the Novartis Foundation, London, 3-5 September 2002"--p. v.0-470-85283-6 Includes bibliographical references and indexes.MOLECULAR CLOCKS AND LIGHT SIGNALLING; Contents; Participants; Chair's introduction; Non-rod, non-cone photoreception in rodents and teleost fish; Discussion; Cryptochromes and inner retinal non-visual irradiance detection; Discussion; General discussion I; Light signalling in Cryptochrome-deficient mice; Discussion; Circadian light input in plants, flies, and mammals; Discussion; Orphan nuclear receptors, molecular clockwork, and the entrainment of peripheral oscillators; Discussion; General discussion; SCN: ringmaster of the circadian circus or conductor of the circadian orchestra?DiscussionOn the communication pathways between the central pacemaker and peripheral oscillators; Discussion; Central and peripheral circadian oscillators in Drosophila; Discussion; Integration of molecular rhythms in mammalian circadian system; Circadian transcriptional output in the SCN and liver of the mouse; Discussion; The molecular workings of the Neurospora biological clock; Discussion; Expression of clock gene products in the suprachiasmatic nucleus in relation to circadian behaviour; Discussion; Circadian rhythms in Drosophila; DiscussionThe role of phosphorylation and degradation of hPer proteins oscillation in normal human fibroblastsDiscussion; Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signalling; Discussion; CK1 and GSK-3 in the Drosophila and mammalian circadian clock; Discussion; Final general discussion; Closing remarks; Index of contributors; Subject indexThe ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their ability to entrain to environmental stimuli. The dominant stimulus comes from environmental light cues, which requires the existence of photopigments sensitive to light. The exact identity of the molecules involved in circadian photoreception has remained elusive. The classical view of the circadian system is of diverse physiological rhythms regulated by a centralized clock structure. This book presentNovartis Foundation symposium ;253.Circadian rhythmsCongressesPhotobiochemistryCongressesElectronic books.Circadian rhythmsPhotobiochemistry571.4571.7/7571.77Chadwick Derek91632Goode Jamie283336MiAaPQMiAaPQMiAaPQBOOK9910143479603321Molecular clocks and light signalling2149283UNINA