04026nam 22006494a 450 991014347820332120170815114957.01-280-27061-697866102706130-470-66758-30-470-85672-60-470-85673-4(CKB)111090529061260(EBL)189592(OCoLC)70928249(SSID)ssj0000117263(PQKBManifestationID)11129461(PQKBTitleCode)TC0000117263(PQKBWorkID)10042760(PQKB)11679410(MiAaPQ)EBC189592(EXLCZ)9911109052906126020031126d2004 uy 0engur|n|---|||||txtccrCancer and inflammation[electronic resource] [Symposium on Cancer and Inflammation, held at the Novartis Foundation, London, 12-14 November 2002 /editors, Derek J. Chadwick (organizer) and Jamie A. Goode]Chichester, U.K. ;Hoboken, N.J. John Wiley & Sons20041 online resource (292 p.)Novartis Foundation symposium ;256Description based upon print version of record.0-470-85510-X Includes bibliographical references and index.CANCER AND INFLAMMATION; Contents; Participants; Chair's introduction; Inflammation and cancer: an epidemiological perspective; Discussion; Chemokine-based pathogenetic mechanisms in cancer; Discussion; General discussion I; Anti-TNFa therapy of rheumatoid arthritis: what can we learn about chronic disease?; Discussion; How do chemokine/chemokine receptor activations affect tumorigenesis?; Discussion; Proinflammatory cytokines, immune response and tumour progression; Discussion; General discussion II; Lymphangiogenesis and tumour metastasis; DiscussionInfiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytesDiscussion; The influence of CD25(+) cells on the generation of immunity to tumour cell-lines in mice; Discussion; Macrophages: modulators of breast cancer progression; Discussion; Chemokines: angiogenesis and metastases in lung cancer; Discussion; Macrophage infiltration and angiogenesis in human malignancy; Discussion; The role of inflammation in tumour growth and tumour suppression; Discussion; Cyclooxygenase 2: from inflammation to carcinogenesisDiscussionThe inflammatory cytokine network of epithelial cancer: therapeutic implications; Discussion; In vivo manipulation of DC migration and activation to elicit anti-tumour immunity; Discussion; Final general discussion; Concluding remarks; Index of contributors; Subject indexChronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and wound healing. The cells involved in inflammation are detected in a range of common cancers, together with the inflammatory cytokines and members of the chemokine ligand/receptor systems.Neutralization or deletion of the gene for some inflammatory cytokines confers resistance to tumour induction and experimental metastasis. Over-expression of such cytokines in tumour cells may enhance malignant potential. Certain chemokines are likely to subvNovartis Foundation symposium ;256.CancerImmunological aspectsCongressesInflammationCongressesElectronic books.CancerImmunological aspectsInflammation571.978616.99/4079616.994079Chadwick Derek91632Goode Jamie283336MiAaPQMiAaPQMiAaPQBOOK9910143478203321Cancer and inflammation1909999UNINA