03158nam 2200637 a 450 991014150680332120200520144314.01-118-40533-11-299-19020-01-118-40535-81-118-40534-X(CKB)2670000000325774(EBL)1120546(OCoLC)792941569(SSID)ssj0000782230(PQKBManifestationID)11455982(PQKBTitleCode)TC0000782230(PQKBWorkID)10735188(PQKB)10792956(MiAaPQ)EBC1120546(Au-PeEL)EBL1120546(CaPaEBR)ebr10658001(CaONFJC)MIL450270(PPN)194585972(EXLCZ)99267000000032577420120424d2013 uy 0engur|n|---|||||txtccrReverse genetics of RNA viruses[electronic resource] applications and perspectives /edited by Anne BridgenChichester, West Sussex John Wiley & Sons20131 online resource (414 p.)Description based upon print version of record.0-470-97965-8 Includes bibliographical references and index.Definitions of reverse genetics, +ve, -ve, sense and doubled stranded (DS) RNA viruses / Anne Bridgen -- Coronavirus reverse genetics / Paul Britton -- Hepatitis C and use of reverse genetics in drug design / Natalia Frias Staheli -- Norovirus reverse genetics / Ian Goodfellow -- Rhabdovirus reverse genetics / Klaus Conzelmann -- Modification of measles virus and application to pathogenesis studies / Paul Duprex -- Bunyavirus reverse genetics and application to interaction with host cells / Richard Elliott -- Influenza A virus vaccines / Wendy Barclay -- Bluetongue virus reverse genetics / Mark Boyce -- Reovirus reverse genetics / Rob Hoeben -- Reverse genetics and quasispecies / Marco Vignuzzi -- Summary and perspectives / Anne Bridgen. Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive RNA virusesReverse geneticsViral proteinsViral vaccinesRNA viruses.Reverse genetics.Viral proteins.Viral vaccines.579.2/5Bridgen Anne1961-873304MiAaPQMiAaPQMiAaPQBOOK9910141506803321Reverse genetics of RNA viruses1949544UNINA