01415nam 2200373Ka 450 991069467540332120051104113313.0(CKB)5470000002363944(OCoLC)62218852(EXLCZ)99547000000236394420051104d2005 ua 0engtxtrdacontentcrdamediacrrdacarrierRussia and NATO[electronic resource] increased interaction in defense research and technology /by Donald C. Daniel and Michael I. Yarymovych[Fort McNair, Washington, D.C.] :Center for Technology and National Security Policy, National Defense University,[2005]6 pages digital, PDF fileDefense horizons ;no. 49Title from title screen (viewed on Nov. 4, 2005)."October 2005."Includes bibliographical references.Russia and NATO EuropeForeign relationsRussiaRussiaForeign relationsEuropeDaniel Donald C(Donald Charles),1944-1191986Yarymovych Michael Ihor1933-1385707National Defense University.Center for Technology and National Security Policy.GPOGPOBOOK9910694675403321Russia and NATO3433681UNINA03038nam 2200817 a 450 991014144940332120200520144314.0978661361917497816219822651621982262978128058934812805893459781118286036111828603097811182860671118286065(CKB)2670000000174713(EBL)843661(OCoLC)787842654(SSID)ssj0000631600(PQKBManifestationID)11428848(PQKBTitleCode)TC0000631600(PQKBWorkID)10599209(PQKB)11154893(MiAaPQ)EBC843661(MiAaPQ)EBC4033812(Au-PeEL)EBL843661(CaPaEBR)ebr10558705(Au-PeEL)EBL4033812(CaPaEBR)ebr11109383(CaONFJC)MIL361917(OCoLC)927507550(iGPub)WILEYB0016391(PPN)17893156X(Perlego)1002763(EXLCZ)99267000000017471320111026d2012 uy 0engur|n|---|||||txtccrAbsorption and drug development solubility, permeability, and charge state /Alex Avdeef2nd ed.Hoboken, N.J. John Wiley & Sonsc20121 online resource (742 p.)Description based upon print version of record.9781118285961 1118285964 9781118057452 1118057457 Includes bibliographical references and index.Introduction -- Transport model -- pKa determination -- Octanol-water partitioning -- Liposome-water partitioning -- Solubility -- Permeability - Pampa -- Permeability Caco 2/MDCK -- Permeability blood brain barrier. Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to analyze drug candidates. Moreover, the author provides expert guidance to help readers analyze the results of their studies in order to select the most promising drug candidates. ThDrugsDesignDrugsMetabolismDrug developmentAbsorptionDrugsDesign.DrugsMetabolism.Drug development.Absorption.615/.19Avdeef Alex521357MiAaPQMiAaPQMiAaPQBOOK9910141449403321Absorption and drug development836551UNINA