02964nam 2200613 a 450 991014128860332120230801222242.01-280-59094-7978661362077497811199429861-118-30540-X1-119-94298-51-119-94297-7(CKB)2670000000170075(EBL)881533(OCoLC)770696945(SSID)ssj0000635051(PQKBManifestationID)11451926(PQKBTitleCode)TC0000635051(PQKBWorkID)10643250(PQKB)11648434(MiAaPQ)EBC881533(DLC) 2012000005(Au-PeEL)EBL881533(CaPaEBR)ebr10630592(CaONFJC)MIL362077(EXLCZ)99267000000017007520111223d2012 uy 0engur|n|---|||||txtccrEvidence synthesis for decision making in healthcare[electronic resource] /Nicky J. Welton ... [et al.]Chichester, West Sussex John Wiley & Sons20121 online resource (296 p.)Statistics in practiceDescription based upon print version of record.0-470-06109-X Includes bibliographical references and index.Introduction -- Bayesian methods and winBUGS -- Introduction to decision models -- Meta-analysis using Bayesian methods -- Exploring between study heterogeneity -- Model critique and evidence consistency in random effects meta-analysis -- Evidence synthesis in a decision modelling framework -- Multi-parameter evidence synthesis in epidemiological models -- Mixed treatment comparisons -- Markov models -- Generalised evidence synthesis -- Expected value of information for research prioritisation and study design.In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixeStatistics in practice.Evidence-based medicineStatistical methodsEvidence-based medicineStatistical methods.362.1068/4Welton Nicky J947329MiAaPQMiAaPQMiAaPQBOOK9910141288603321Evidence synthesis for decision making in healthcare2140410UNINA