04433nam 2200625 a 450 991014126860332120230801222428.01-280-59208-797866136219171-118-25992-01-118-26000-71-118-25946-7(CKB)2670000000175333(EBL)836583(OCoLC)785811589(SSID)ssj0000639765(PQKBManifestationID)11432621(PQKBTitleCode)TC0000639765(PQKBWorkID)10610955(PQKB)11669620(MiAaPQ)EBC836583(MiAaPQ)EBC4033578(Au-PeEL)EBL836583(CaPaEBR)ebr10558136(CaONFJC)MIL362191(EXLCZ)99267000000017533320111005d2012 uy 0engur|n|---|||||txtccrPlant bioactives and drug discovery[electronic resource] principles, practice, and perspectives /edited by Valdir Cechinel-FilhoHoboken, N.J. John Wiley & Sonsc20121 online resource (594 p.)Wiley series in drug discovery and developmentDescription based upon print version of record.0-470-58226-X Includes bibliographical references and index.Natural products in drug discovery : recents advances / Gordon M. Cragg, Paul G. Grothaus, David J. Newman -- Modern approaches in the search for new active compounds from crude extracts of natural sources / Emerson F. Queiroz, Kurt Hostettmann, Jean-Luc Wolfender -- Natural product as lead compounds in medicinal chemistry / Eliezer J. Barreiro, Carlos A.M. Fraga, Lidia M. Lima -- The importance of structural manipulation of natural compounds in drug discovery and development / Arturo San Feliciano ... [et al.] -- The action of plants and their constituents on the central nervous system / Fulvio R. Mendes ... [et al.] -- The role of natural products in discovery of new anti-infective agents with emphasis on antifungal compounds / Maximiliano Sortino ... [et al.] -- Antiulcer agents from higher plants / Luiz C. Klein-Junior, José R. Santin, Sérgio F. de Andrade -- Recent progress in the chemistry and biology of paclitaxel (Taxol) and related taxanes / Jun Qi, Jielu Zhao, David G.I. Kingston -- Cancer chemopreventive activity of higher plants / A. Douglas Kinghorn ... [et al.] -- Medicinal plants and pharmaceutical technology / Ruth M. Lucinda da Silva, Angélica G. Couto, Tania M.B. Bresolin -- Natural products in clinical trials / Sigrun Chrubasik -- The influence of biotic and abiotic factors on the production of secondary metabolites in medicinal plants / Dayana R. Gouveia, Leonardo Gobbo-Neto, Norberto P. Lopes -- Production of bioactives compounds : the importance of Pictet-Spengler reaction in the XXI century / Pilar Menendez ... [et al.] -- Screening methods for drug discovery from plants / Alan L. Harvey -- Phytotherapeutics: intellectual property rights, global market, and global regulatory guidelines / James D. McChesney, Raymond Cooper, Kip Vought -- Cooperation between the pharmaceutical industry and academic institutions in drug discovery / Valdir Cechinel Filho, Rivaldo Niero, and Rosendo A. Yunes. An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of Wiley series in drug discovery and development.Medicinal plantsPlant bioactive compoundsMedicinal plants.Plant bioactive compounds.615.3/21Cechinel-Filho Valdir923736MiAaPQMiAaPQMiAaPQBOOK9910141268603321Plant bioactives and drug discovery2073064UNINA