05500nam 2200673 450 991014046200332120230807210355.01-118-64058-61-118-64056-X(CKB)2670000000613905(EBL)2036180(SSID)ssj0001498010(PQKBManifestationID)11874268(PQKBTitleCode)TC0001498010(PQKBWorkID)11501893(PQKB)10689740(MiAaPQ)EBC3059102(MiAaPQ)EBC2036180(DLC) 2015005256(Au-PeEL)EBL3059102(CaPaEBR)ebr11050662(CaONFJC)MIL778968(OCoLC)922954958(EXLCZ)99267000000061390520150202d2015 uy| 0engur|||||||||||txtccrOveractive bladder practical management /edited by Jacques Corcos, Scott MacDiarmid, John HeesakkersChichester, West Sussex, United Kingdom ;Hoboken, New Jersey :John Wiley & Sons,2015.1 online resource (272 p.)Description based upon print version of record.1-118-64059-4 1-118-64061-6 Includes bibliographical references and index.Title Page; Copyright Page; Contents; Contributors; Foreword; Foreword: The impact of Overactive Bladder on Urogynecology; Foreword; Preface; Section 1 Introduction; Chapter 1 Overactive bladder: terminology and problem spectrum; References; Chapter 2 Pathophysiology; Introduction; The innervation of the bladder; The genesis of the NDO: three hypothesis; The link to the clinic; The neurological pathologies responsible for the development of the neurogenic bladder; Histological changes; Conclusions; References; Section 2 Evaluation; Chapter 3 Timing for evaluation; Conclusion; ReferencesChapter 4 Clinical evaluation Introduction; History; Neurological history; General gynecological history; Obstetric history; Other relevant past medical and surgical history; Drug history; Examination; Questionnaires and quality of life; Summary; References; Chapter 5 Urodynamic evaluation of the overactive bladder; Introduction; OAB and urodynamics; Filling cystometry and OAB; Cystometrogram; Does OAB equal urodynamic DO? A clinical correlation; Pressure-flow studies and OAB; Summary; References; Chapter 6 Other testing; Bladder/detrusor wall thickness; Biomarkers; Near infrared spectroscopyBladder wall strain imaging Autonomic nervous system; Functional brain imaging; Conclusions; References; Section 3 First Line Management; Chapter 7 Changes in lifestyle; Introduction; Lifestyle modifications; Obesity; Smoking; Extremes of daily fluid intake; Dietary bladder irritants; Constipation and straining at stool; Summary; References; Patient Guide 1 Lifestyle changes that can improve bladder symptoms; Maintain a healthy weight; Stop smoking; Moderate liquid and beverage intake; Monitor your diet; Maintain bowel regularity; Chapter 8 Physical therapy; Physical therapyScheduled voiding/bladder training Pelvic floor muscle training; Electrical stimulation; References; Section 4 Second Line Management; Chapter 9 Oral medication for overactive bladder; Introduction; Antimuscarinics; Beta 3 (β3) adrenergic receptor (AR) agonists; Antidepressants; References; Chapter 10 Patches and gels; Rationale for TD OXY delivery; Drug pharmacology; Conclusion/expert opinion; References; Chapter 11 Promising experimental drugs and drug targets; Introduction; P2X3-receptors and P2X3 receptor antagonists; The cannabinoid system; TRP channels; ReferencesChapter 12 The role of co-medication in the treatment of OAB Introduction; Antimuscarinics and α-adrenoreceptor antagonists; Phosphodiesterase-5 inhibitors and α-adrenoreceptor antagonists; Other combination regimens; Future directions; References; Chapter 13 Other non-surgical approaches for the treatment of overactive bladder; Introduction; Bladder training; Acupuncture; Naturopathic and herbal remedies; Magnetic stimulation; Containment products; Future: tissue engineering and gene therapy; Conclusion; Abbreviations; Financial and competing interests disclosure; ReferencesSection 5 Third Line ManagementOveractive Bladder: Practical Management provides urologists, gynecologists and other health practitioners with a comprehensive clinical guide to this very common problem, resulting in a perfect resource to consult time and time again. Beginning with an introductory section covering the definition and pathophysiolgy of OAB, it then moves on to cover evaluation, first-line management, second-line management and finally surgery. Well-illustrated throughout, each chapter begins with a key points box outlining the most important take-home messages. Also included are clear management algorithmsUrinary incontinenceTreatmentBladderDiseasesTreatmentUrinary incontinenceTreatment.BladderDiseasesTreatment.616.6/2Corcos JacquesMacDiarmid Scott A.Heesakkers JohnMiAaPQMiAaPQMiAaPQBOOK9910140462003321Overactive bladder1984648UNINA