05830nam 22010213u 450 991013961410332120220822173102.01-283-20458-497866132045851-119-97940-41-119-97937-4(CKB)2550000000042729(EBL)697592(OCoLC)746598464(SSID)ssj0000535620(PQKBManifestationID)12234237(PQKBTitleCode)TC0000535620(PQKBWorkID)10522354(PQKB)10434098(MiAaPQ)EBC697592(EXLCZ)99255000000004272920131014d2011|||| u|| |engur|n|---|||||txtccrCurrent and Future Issues in Hemophilia Care /edited by Emérito-Carlos Rodríguez-Merchán, Leonard A. ValentinoHoboken Wiley20111 online resource (190 p.)Description based upon print version of record.0-470-67057-6 Current and Future Issues in Hemophilia Care; Contents; List of Contributors; Preface; Part 1: Introduction; 1 History of Hemophilia; 2 Hemophilia Care in the Modern World; 3 Comprehensive Care Model in Hemophilia; Part 2: General Topics; 4 When Should We Switch from On-Demand to Prophylaxis Regimen?; 5 Prophylaxis in Children; 6 Prophylaxis in Adults with Hemophilia; 7 The Economics of Prophylaxis: Does Prophylaxis with Clotting Factor Represent Value for Money?; 8 The Transition of Care for the Young Adult Hemophilia Patient; 9 Perinatal Clinical Care and Molecular Diagnosis in Hemophilia10 Managing the Mature Person with Hemophilia11 Quality of Life in Hemophilia; Part 3: Inhibitors; 12 Immunology of Inhibitor Development; 13 Epidemiology of Inhibitors; 14 Early Tolerization to Minimize Inhibitors in PUPs with Hemophilia A; 15 Prediction of Inhibitors in Severe Hemophilia; 16 Genetic Basis for Inhibitor Development; 17 Non-Genetic Risk Factors for Inhibitor Development; Part 4: Inhibitor Treatment; 18 Immune Tolerance Induction Programs; 19 Prophylaxis in Hemophilia A Patients with Inhibitors; 20 Treatment of Bleeding in FVIII Inhibitor Patients21 Discordancy of Bypassing Therapy Part 5: Joint Health and Disease; 22 Experimental Studies on Hemarthrosis, Synovitis and Arthropathy; 23 Assessment of Joint Involvement in Hemophilia; 24 Imaging of the Hemophilic Joint; 25 Initial and Advanced Stages of Hemophilic Arthropathy, and Other Musculo-Skeletal Problems: The Role of Orthopedic Surgery; 26 Perioperative Thromboprophylaxis for Persons with Hemophilia Undergoing Orthopedic Surgery; Part 6: New Developments; 27 New Technologies for the Pharmacokinetic Improvement of Coagulation Factor Proteins28 Current and Future Approaches to Gene Therapy in Patients with Hemophilia29 New Developments in Hemophilic Arthropathy; 30 Physiotherapy Evaluation and Intervention in the Acute Hemarthrosis: Challenging the Paradigm; 31 Laboratory Assays to Predict Response to Bypassing Agents; 32 Combination/Sequential Use of Bypassing Agents; IndexAs haemophilia is a life-long condition, continuing supervision by a group of medical personnel is required. In many countries this is provided by comprehensive care haemophilia centres where staff of all specialities concerned with treatment- haematologists, paediatricians, nurses, physiotherapists, orthopaedic surgeons - have specialized knowledge. This new book is a definitive resource on the current aspects and issues around haemophilia. Complications of haemophilia care are well covered in chapters on inhibitors, and musculoskeletal problems, as are all the latest developments in theBlood Coagulation FactorsHemophiliaHemorrhagic DisordersBlood Coagulation Disorders, InheritedBiological FactorsCoagulation Protein DisordersBlood ProteinsBlood Coagulation DisordersProteinsGenetic Diseases, InbornHematologic DiseasesHemic and Lymphatic DiseasesAmino Acids, Peptides, and ProteinsCongenital, Hereditary, and Neonatal Diseases and Abnormalities /edited by Emérito-Carlos Rodríguez-Merchán, Leonard A. ValentinoDiseasesHemophilia ABlood Coagulation FactorsMedicineHILCCHealth & Biological SciencesHILCCHematologic DiseasesHILCCBlood Coagulation Factors.HemophiliaHemorrhagic DisordersBlood Coagulation Disorders, InheritedBiological FactorsCoagulation Protein DisordersBlood ProteinsBlood Coagulation DisordersProteinsGenetic Diseases, InbornHematologic DiseasesHemic and Lymphatic DiseasesAmino Acids, Peptides, and ProteinsCongenital, Hereditary, and Neonatal Diseases and Abnormalities /DiseasesHemophilia ABlood Coagulation FactorsMedicineHealth & Biological SciencesHematologic Diseases600616.1572Rodriguez-Merchan E. C.Valentino Leonard A.AU-PeELAU-PeELAU-PeELBOOK9910139614103321Current and Future Issues in Hemophilia Care2904953UNINA