03550nam 2200601Ia 450 991013947290332120170815170042.01-282-68281-497866126828103-527-62958-03-527-62959-9(CKB)2550000000006848(EBL)481246(OCoLC)587380638(SSID)ssj0000356857(PQKBManifestationID)11269912(PQKBTitleCode)TC0000356857(PQKBWorkID)10350096(PQKB)10581696(MiAaPQ)EBC481246(NjHacI)992550000000006848(PPN)164070117(EXLCZ)99255000000000684820040521d2010 uy 0engur|n|---|||||txtccrAtherosclerosis[electronic resource] molecular and cellular mechanisms /edited by Sarah Jane George and Jason JohnsonWeinheim Wiley-VCH Verlag GmbH & Co.20101 online resource (422 p.)Description based upon print version of record.3-527-32448-8 Includes bibliographical references and index.Atherosclerosis: Molecular and Cellular Mechanisms; Contents; Preface; List of Contributors; PART I: Introduction; 1: Pathogenesis of Atherosclerosis; PART II: PRO-Inflammatory Factors; 2: Chemokines and Atherosclerosis: A Critical Assessment of Therapeutic Targets; 3: Adhesion Molecules and Atherosclerosis; 4: Cytokines and Atherosclerosis; 5: Toll-Like Receptors in Atherosclerosis; 6: PPAR-Based Therapies for the Management of Atherosclerosis; 7: Pentraxins in Vascular Pathology: The Role of PTX3; PART III: Proteases; 8: Metalloproteinases, the Endothelium, and Atherosclerosis9: Cathepsins in Atherosclerosis10: The Plasmin System and Atherosclerosis; 11: Mast Cell Proteases and Atherosclerosis; PART IV: Hyperlipidemia; 12: Macrophage Foam Cell Formation: The Pathways to Cholesterol Engorgement; PART V: Oxidative Stress; 13: NADPH Oxidase and Atherosclerosis; 14: Uncoupling of Endothelial Nitric Oxide Synthase in Atherosclerosis; 15: Heme Oxygenase-1 and Atherosclerosis; PART VI: Cell Growth and Phenotype; 16: Phenotypic Heterogeneity of Smooth Muscle Cells-Implications for Atherosclerosis17: Platelets: Their Role in Atherogenesis and Thrombosis in Coronary Artery Disease18: Modulators of Monocyte and Macrophage Phenotypes in Atherosclerosis; IndexWith atherosclerosis being the number one cause of death in the western world, this handbook and ready reference provides a comprehensive account of the different stages and factors in the development of the atherosclerotic plaque. Each chapter is written by experts in the field and highlights the role of specific mediators of atherosclerotic plaque development, as well as potential therapeutic targets. A large amount of this up-to-date information is conveyed by way of tables and schematic figures, in a readily comprehensible manner. A must-have for master and PhD students, researcherAtherosclerosisArteriesDiseasesAtherosclerosis.ArteriesDiseases.616.136George Sarah JaneJohnson JasonMiAaPQMiAaPQMiAaPQBOOK9910139472903321Atherosclerosis729078UNINA