04632nam 2200625 a 450 991013923490332120230803023600.01-118-54346-71-118-54349-11-299-27761-61-118-54348-3(CKB)2560000000099152(EBL)1138223(OCoLC)850198956(SSID)ssj0000835973(PQKBManifestationID)11516246(PQKBTitleCode)TC0000835973(PQKBWorkID)10996967(PQKB)10202076(MiAaPQ)EBC1138223(Au-PeEL)EBL1138223(CaPaEBR)ebr10667405(CaONFJC)MIL459011(EXLCZ)99256000000009915220121102d2013 uy 0engur|n|---uuuuutxtrdacontentcrdamediacrrdacarrierQuality in laboratory hemostasis and thrombosis[electronic resource] /edited by Steve Kitchen, John D. Olson, F. Eric Preston ; foreword by Frits R. Rosendaal2nd ed.Chichester [England] Wiley-Blackwell20131 online resource (xii, 278 pages) illustrationsDescription based upon print version of record.0-470-67119-X Includes bibliographical references and index.General quality planning in the hemostasis laboratory / John D. Olson -- Hemostasis test validation, performance, and reference intervals : international recommendations and guidelines / Richard A. Marlar -- Causes of errors in medical laboratories / Giuseppi Lippi, Emmanuel J. Favaloro -- International standards in hemostasis / Trevor W. Barrowcliffe, Anthony R. Hubbard -- Sample integrity and pre-analytical variables / Dorothy (Adcock) Funk -- Internal quality control in the hemostasis laboratory / Steve Kitchen, F. Eric Preston, John D. Olson -- External quality assessment in hemostasis : its importance and significance / F. Eric Preston, Steve Kitchen, Alok Srivastava -- The unique challenges of hemostatic testing in children / M. Patricia Massicotte ... [et al.] -- Initial evaluation of hemostasis : reagent and method selection / Wayne L. Chandler -- Assay of factor VIII and other clotting factors / Steve Kitchen, F. Eric Preston -- Application of molecular genetics to the investigation of inherited bleeding disorders / Stefan Lethagen, Morten Dunø, Lars Bo Nielsen -- Detecting and quantifying acquired functional inhibitors in haemostasis / Bert Verbruggen, Myriam Dardikh, Britta Laros-van Gorkom --Standardisation of D-dimer testing / Guido Reber, Philippe de Moerloose -- Point-of-care testing in hemostasis / Chris Gardiner ... [et al.] -- Diagnostic assessment of platelet function / Paquita Nurden, Alan Nurden, Martine Jandrot-Perrus -- Laboratory evaluation of heparin-induced thrombocytopenia / Theodore (Ted) E. Warkentin, Jane C. Moore -- Laboratory evaluation of von Willebrand disease : phenotypic analysis / Emmanuel J. Favaloro -- Laboratory analysis of von Willebrand disease : molecular analysis / Anne C. Goodeve, Ian R. Peake -- Quality issues in heritable thrombophilia testing / Isobel D. Walker, Ian Jennings -- Evaluation of antiphospholipid antibodies / Michael Greaves -- Monitoring heparin therapy / Marilyn Johnston -- Monitoring oral anticoagulant therapy with vitamin K antagonists / Armando Tripodi -- Monitoring new anticoagulants / Elaine Gray, Steve Kitchen.The hemostasis laboratory has a vital role in the diagnosis and management of patients with familial and acquired haemorrhagic and thrombotic disorders. Its role in the monitoring of traditional anticoagulant therapy, as well as therapy using new anticoagulants, presents new challenges to the laboratory. This new edition addresses these important issues, as well as international guidelines for testing, the development of international standard materials, management of haemostasis testing from the laboratory to the point-of-care, and molecular genetic testing.HemostasisLaboratory manualsThrombosisLaboratory manualsHemostasisThrombosis616.1/57075Kitchen Steve(Scientist)860323Olson John David1944-860324Preston F. E860325MiAaPQMiAaPQMiAaPQBOOK9910139234903321Quality in laboratory hemostasis and thrombosis1919643UNINA04826nam 22006855 450 991030010810332120251116195837.03-319-76895-610.1007/978-3-319-76895-3(CKB)4100000004243748(DE-He213)978-3-319-76895-3(MiAaPQ)EBC5403425(PPN)227402510(EXLCZ)99410000000424374820180525d2018 u| 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierAsymptotics of Elliptic and Parabolic PDEs and their Applications in Statistical Physics, Computational Neuroscience, and Biophysics /by David Holcman, Zeev Schuss1st ed. 2018.Cham :Springer International Publishing :Imprint: Springer,2018.1 online resource (XXIII, 444 p. 103 illus., 56 illus. in color.)Applied Mathematical Sciences,0066-5452 ;1993-319-76894-8 Part I. Singular Perturbations of Elliptic Boundary Problems -- 1 Second-Order Elliptic Boundary Value Problems with a Small Leading Part -- 2 A Primer of Asymptotics for ODEs -- 3 Singular Perturbations in Higher Dimensions -- 4 Eigenvalues of a Non-self-adjoint Elliptic Operator -- 5 Short-time Asymptotics of the Heat Kernel -- Part II Mixed Boundary Conditions for Elliptic and Parabolic Equations -- 6 The Mixed Boundary Value Problem -- 7 THe Mixed Boundary Value Problem in R2 -- 8 Narrow Escape in R3 -- 9 Short-time Asymptotics of the Heat Kernel and Extreme Statistics of the NET -- 10 The Poisson–Nernst–Planck Equations in a Ball -- 11 Reconstruction of Surface Diffusion from Projected Data -- 12 Asymptotic Formulas in Molecular and Cellular Biology -- Bibliography -- Index.This is a monograph on the emerging branch of mathematical biophysics combining asymptotic analysis with numerical and stochastic methods to analyze partial differential equations arising in biological and physical sciences. In more detail, the book presents the analytic methods and tools for approximating solutions of mixed boundary value problems, with particular emphasis on the narrow escape problem. Informed throughout by real-world applications, the book includes topics such as the Fokker-Planck equation, boundary layer analysis, WKB approximation, applications of spectral theory, as well as recent results in narrow escape theory. Numerical and stochastic aspects, including mean first passage time and extreme statistics, are discussed in detail and relevant applications are presented in parallel with the theory. Including background on the classical asymptotic theory of differential equations, this book is written for scientists of various backgrounds interested in deriving solutions to real-world problems from first principles.Applied Mathematical Sciences,0066-5452 ;199Differential equations, PartialMathematical physicsPhysicsBiomathematicsBiophysicsBiophysicsPartial Differential Equationshttps://scigraph.springernature.com/ontologies/product-market-codes/M12155Mathematical Applications in the Physical Scienceshttps://scigraph.springernature.com/ontologies/product-market-codes/M13120Numerical and Computational Physics, Simulationhttps://scigraph.springernature.com/ontologies/product-market-codes/P19021Mathematical and Computational Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/M31000Mathematical Methods in Physicshttps://scigraph.springernature.com/ontologies/product-market-codes/P19013Biological and Medical Physics, Biophysicshttps://scigraph.springernature.com/ontologies/product-market-codes/P27008Differential equations, Partial.Mathematical physics.Physics.Biomathematics.Biophysics.Biophysics.Partial Differential Equations.Mathematical Applications in the Physical Sciences.Numerical and Computational Physics, Simulation.Mathematical and Computational Biology.Mathematical Methods in Physics.Biological and Medical Physics, Biophysics.515.353Holcman Davidauthttp://id.loc.gov/vocabulary/relators/aut768213Schuss Zeevauthttp://id.loc.gov/vocabulary/relators/autBOOK9910300108103321Asymptotics of Elliptic and Parabolic PDEs2018996UNINA