02675nam 2200613Ia 450 991013901880332120200520144314.01-118-35447-81-118-35448-61-299-46484-X1-118-35446-X(CKB)2550000001019352(EBL)1166776(OCoLC)806456447(SSID)ssj0000856037(PQKBManifestationID)11470379(PQKBTitleCode)TC0000856037(PQKBWorkID)10805077(PQKB)11433918(MiAaPQ)EBC1166776(DLC) 2012033430(Au-PeEL)EBL1166776(CaPaEBR)ebr10687828(CaONFJC)MIL477734(PPN)178874191(EXLCZ)99255000000101935220120813d2013 uy 0engur|n|---|||||txtccrDrug discovery[electronic resource] practices, processes, and perspectives /edited by Jie Jack Li, E.J. CoreyHoboken, N.J. John Wiley & Sonsc20131 online resource (572 p.)Description based upon print version of record.0-470-94235-5 Includes bibliographical references and index.History of drug discovery -- Target identification and validation -- In vitro and in vivo assays -- Drug metabolism and pharmacokinetics in drug discovery -- Cardiovascular drugs -- Diabetes drugs -- CNS drugs -- Cancer drugs -- Antiinflammatory and immunomodulatory drugs -- Anti-bacterial drugs -- Antiviral drug discovery. Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design.<pDrug developmentPharmaceutical chemistryDrug development.Pharmaceutical chemistry.615.1/9Li Jie Jack440094Corey E. J20674MiAaPQMiAaPQMiAaPQBOOK9910139018803321Drug discovery2192429UNINA