02079oam 2200385z 450 991013774930332120240606204201.097895351662219535166220(CKB)3230000000076480(Perlego)2011224(oapen)doab65402(EXLCZ)99323000000007648020150504d2012uuuu -u 0engurmn|---annantxtrdamediacrdamediaordacarrierMuscle Biopsy /edited by Challa SundaramInTech1 online resource9789533077789 9533077786 "Investigation of muscle diseases has changed dramatically with the understanding of genetic basis of a wide range of muscle diseases. Muscle biopsy has become a powerful tool not only to provide diagnosis but to make tissue available for genetic studies and to basic scientists for biomedical research. Accurate interpretation of muscle biopsy to detect cell dysfunction/ damage/death or absence / abnormality of a protein or genetic defect by the sophisticated technologies is important to guide treatment of various muscle diseases. In this book on muscle biopsy various chapters deal with the procedure and interpretation of muscle biopsy, its use in the culture of myotubes and membrane transport studies.Muscle biopsy is an important technique to investigate mitochondrial dysfunction and the mitochondrial DNA integrity in oxidation. Phosphorylation in various metabolic diseases like obesity, type 2 diabetes mellitus and peripheral vascular disease is explored in the other chapters with detailed descriptions on methodology. This book provides the advances in the basic techniques of muscle biopsy for a neuroscientist."BiopsyMusclesHistopathologyBiopsy.Muscles.Sundaram Challa909602BOOK9910137749303321Muscle Biopsy2035378UNINA