03183nam 2200625zu 450 991013719620332120240424225743.09782889194025 (ebook)(CKB)3710000000526123(SSID)ssj0001680083(PQKBManifestationID)16496096(PQKBTitleCode)TC0001680083(PQKBWorkID)15028246(PQKB)11164022(WaSeSS)IndRDA00057155(oapen)https://directory.doabooks.org/handle/20.500.12854/44933(oapen)doab44933(EXLCZ)99371000000052612320160829d2015 uy |engur|||||||||||txtccrDeveloping stem cell-based therapies for neural repair /topic editors Clare Parish and Lachlan ThompsonFrontiers Media SA2015France :Frontiers Media SA,20151 online resource (114 pages) illustrations, chartsFrontiers Research Topics,1664-8714Bibliographic Level Mode of Issuance: MonographIncludes bibliographical references.Current pharmacotherapies and surgical intervention provide limited benefit in the treatment of neural injuries or halting disease progression and has resulted in significant hope for the successes of stem cell research. The properties of stem cells render them appropriate for cell replacement therapy, endogenous repair, disease modeling as well as high-throughput drug screening and development. Such applications will aide in increasing our knowledge and developing treatments for neurodegenerative disorders such as Parkinson’s disease and Huntington’s diseases as well as neural traumas including ischemic brain damage and traumatic brain injury. This Frontiers Research topic encouraged contributions from the general field of stem cell biology, with a particular emphasis on utilizing these cells to develop new therapies for neural repair. Related articles deal with issues such as: breakthroughs in stem cell proliferation/differentiation methodologies, using pluripotent and neural stem cells for transplantation and endogenous repair, the use of patient derived stem cells for disease modeling, using stem cells for drug discovery as well as the ethical issues related to the use of stem cells.CytologyHILCCBiologyHILCCHealth & Biological SciencesHILCCStem CellsPluripotent Stem Cellsdisease modellingdrug disoveryTransplantationNerve Tissue ProteinsEmbryonic Stem CellsNeural RepairCytologyBiologyHealth & Biological Sciences616.02/774Lachlan Thompsonauth1365479Parish ClareThompson LachlanPQKBUkMaJRU9910137196203321Developing stem cell-based therapies for neural repair3387418UNINA