03083nam 2200589 450 991013709960332120230807212030.0(CKB)3710000000824699(oapen)https://directory.doabooks.org/handle/20.500.12854/40880(EXLCZ)99371000000082469920160822d2015uuuu fu| 0engurc|#---|||||txtrdacontentcrdamediacrrdacarrierAnimal allergens[electronic resource] common protein characteristics featuring their allergenicity /edited by Christiane Hilger and Annette KuehnFrontiers Media SA2015[Place of publication not identified] :Frontiers Media SA,2015.1 online resource (88 pages) illustrations; digital, PDF file(s)Frontiers research topicsFrontiers in immunologyPublished in: Frontiers in immunology.2-88919-620-8 Includes bibliographical references.Among the many molecules present in our environment, some have the property to induce allergic sensitization and IgE-mediated reactions. The analysis of known major animal allergens has shown that most belong to single protein families: lipocalins and serum albumins for inhalant allergens, EF-hand proteins, tropomyosins and caseins for the digestive allergens. The finding that allergens are often clustered in large families may be related to the fact that common structural, biochemical or functional features contribute to their allergenicity, in addition to external adjuvant factors. Currently, there is no curative treatment for animal allergy available. In order to lower allergic reactions to respiratory allergens in daily life and to food allergens upon accidental exposure, it is important to desensitize concerned patients. Tolerance induction by allergen-specific immunotherapy is in the current focus of an ambitious research. This Research Topic aims to provide a comprehensive view of the basic and recent insights on the allergenicity of animal allergens in view of their structural and functional aspects as well as allergen-specific immunotherapy.Frontiers in immunology.Immunologic diseasesAllergensAllergy and immunologyAllergensimmunologyallergen exposureisoallergensimmune responseImmunotherapybiological functionallergycross-reactivityAllergenicityAnimal allergenImmunologic diseases.Allergens.Allergy and immunology.Allergensimmunology.Christiane Hilgerauth1376539Hilger ChristianeKuehn AnnetteUkMaJRUBOOK9910137099603321Animal allergens3412434UNINA