01701nam 2200469 n 450 99639332510331620221108021727.0(CKB)4940000000111524(EEBO)2240953413(UnM)99868953(EXLCZ)99494000000011152419940711d1659 uy |engurbn||||a|bb|Organon salutis[electronic resource] an instrument to cleanse the stomach. As also divers new experiments of the virtue of tobacco and coffee: how much they conduce to preserve humane health. /By W.R. of Gray's Inne, EsquireThe second edition, with new additions.London Printed for D. Pakeman, at the Rainbow in Fleet-street, neer the Inner Temple Gate1659[24], 68 pDedication signed: Will. Rumsey.Includes letters from Henry Blount and James Howell.Annotation on Thomason copy: "July.".Reproduction of the original in the British Library.eebo-0018MedicineEarly works to 1800TobaccoEarly works to 1800CoffeeEarly works to 1800DigestionEarly works to 1800MedicineTobaccoCoffeeDigestionW. R(Walter Rumsey),1584-1660.1009148Blount HenrySir,1602-1682.1001719Howell James1594?-1666.508777Cu-RivESCu-RivESCStRLINWaOLNBOOK996393325103316Organon salutis2329392UNISA04714nam 2200469z- 450 991013709330332120210211(CKB)3710000000824726(oapen)https://directory.doabooks.org/handle/20.500.12854/52767(oapen)doab52767(EXLCZ)99371000000082472620202102d2015 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMarine BiomoleculesFrontiers Media SA20151 online resource (97 p.)Frontiers Research Topics2-88919-661-5 Oceans include the greatest extremes of pressure, temperature and light, and habitats can range from tropical waters to ocean trenches, several kilometers below sea level at high pressure. With its 70% of the surface of our planet marine ecosystem still remains largely unexplored, understudied and underexploited in comparison with terrestrial ecosystems, organisms and bioprocesses. The biological adaptation of marine organisms to a wide range of environmental conditions in the specific environment (temperature, salinity, tides, pressure, radiation, light, etc.) has made them an enormous reservoir of interesting biological material for both basic research and biotechnological improvements. As a consequence marine ecosystem is valued as a source of enzymes and other biomolecules exhibiting new functions and activities to fulfill human needs. Indeed, in recent years it has been recognised as an untapped source of novel enzymes and metabolites even though, with regard to the assignment of precise biological functions to genes, proteins and enzymes, it is still considered as the least developed. Using metagenomics to recover genetic material directly from environmental samples, this biogenetic diversification can be accessed but despite the contributions from metagenomic technologies the new field requires major improvements. A few words on the complexity of marine environments should be added here. This complexity ranges from symbiotic relationships to biology and chemistry of defence mechanisms and from chemoecology of marine invasions up to the strategies found in prokaryotes to adapt to extreme environments. The interdisciplinary study of this complexity will enable researchers to find an arsenal of enzymes and pathways greatly demanded in biotechnological applications. As far as marine enzymes are concerned they may carry novel chemical and stereochemical properties, thus biocatalytically oriented studies (testing of suitable substrates, appropriate checking of reaction conditions, study of stereochemical asset of catalysis) should be performed to appropriately reveal this "chemical biodiversity" which increases interest for these enzymes. Among other biomolecules, polysaccharides are the most abundant renewable biomaterial found on land and in oceans. Their molecular diversity is very interesting; except polysaccharides used traditionally in food and non-food industries, the structure and the functionality of most of them are unknown and unexplored. Brown seaweeds synthesize unique bioactive polysaccharides: laminarans, alginic acids and fucoidans. A wide range of biological activities (anticoagulant, antitumor, antiviral, anti-inflammation, etc.) have been attributed to fucoidans and their role with respect to structure-activity relationship is still under debate. In this Research Topic, we wish to centralize and review contributions, idea and comments related to the issues above. In particular results of enzymatic bioprospecting in gross marine environment will be acknowledged along with research for structural characterization and biological function of biomolecules such as marine polysaccharides and all kind of research related to the complexity of bioprocesses in marine environments. Inter- and multi-disciplinary approach to this field is favoured in this Research Topic and could greatly be facilitated by the web and open access nature as well.Chemistrybicsscalgae and microalgaeBiodiversityBiofuelsmarine bioprocessesMarine enzymesMarine Natural Productsmarine polysaccharidesOlfactionsulfatasetriterpene glycosidesChemistryAntonio Trinconeauth1303419Mikhail KusaykinauthSvetlana ErmakovaauthBOOK9910137093303321Marine Biomolecules3027022UNINA