03322nam 2200613 450 991013708920332120230621141056.0(CKB)3710000000824749(oapen)https://directory.doabooks.org/handle/20.500.12854/54506(EXLCZ)99371000000082474920160822h20152015 fy| 0engur||#---|||||txtrdacontentcrdamediacrrdacarrierNeuroinflammation and behaviour /edited by: Luba Sominsky, Adam K. Walker and Deborah M. HodgsonFrontiers Media SA2015[Lausanne, Switzerland] :Frontiers Media SA,2015.©20151 online resource (136 pages) illustrations; digital file(s)Frontiers Research TopicsFrontiers in Neuroscience2-88919-602-X Includes bibliographical references.The brain and immune system are involved in an intricate network of bidirectional communication. This relationship is vital for optimal physiological and psychological development and functioning but can also result in unwanted outcomes. In particular, this interaction plays an important role in cognition, mood and behaviour. Neuroinflammation is known to contribute to neurological and affective disorders including impaired learning and memory, depressive, anxiety and schizoaffective symptoms, as well as pain. The development of these conditions often occurs on the backdrop of pre-existing physical illnesses which give rise to increased activation of the immune system, such as cancer, obesity, infection and autoimmune disorders. Similarly, psychological states can alter regulation of the immune system. This has been most extensively studied in the context of stress and immune function. Understanding the underlying mechanisms that lead to the onset of inflammation-induced neuropathology and stress-induced immune suppression will lead to the development of novel and effective treatment strategies for both the disease and its neurological side effects. The aim of this research topic is to explore the relationship between the immune system and the brain throughout life from the developing infant to the ageing individual.Frontiers research topics.Frontiers in neuroscience.NeuroimmunologyNervous systemDiseasesImmunological aspectsNervous System DiseasesimmunologyneuroimmuneObesityneuroendocrineproinflammatoryAgingNeuroinflammationDepressionMood DisordersMicrogliaPerinatal programmingNeuroimmunology.Nervous systemDiseasesImmunological aspects.Nervous System Diseasesimmunology.Deborah M. Hodgsonauth1366252Sominsky LubaWalker Adam K.Hodgson Deborah M.Frontiers Research Foundation,UkMaJRUBOOK9910137089203321Neuroinflammation and behaviour3388736UNINA