03243nam 2200529 450 9910136584103321(CKB)3710000000903214(EBC)4717915(OCoLC)962195173(CaBNvSL)swl00406910(MiAaPQ)EBC4717915(EXLCZ)99371000000090321420161105d2017 fy 0engurcnu||||||||rdacontentrdamediardacarrierNerve disease ALS and gradual loss of muscle function amytrophic lateral sclerosis /Mary E. MillerFirst edition.New York, [New York] (222 East 46th Street, New York, NY 10017) :Momentum Press,2017.1 online resource (xiii, 39 pages) illustrationsHuman diseases and conditions collectionIncludes bibliographical references (pages 27-29) and index.1. Symptoms and diagnosis -- 2. Causes and contributing factors -- 3. Treatment and therapy -- 4. Future prospects -- Conclusion -- Bibliography -- Glossary -- About the author -- Index.Amyotrophic lateral sclerosis, ALS, is a common form of motor neuron disease that involves a loss of function in upper and lower motor neurons. ALS causes a progressive loss of muscle function that frequently initiates in the limbs, called limb-onset ALS, or initiates in facial muscles, called bulbar-onset ALS. This book describes the current understanding of ALS symptoms, diagnosis, causes, and treatments. Initial symptoms vary in type of muscle dysfunction, intensity of symptoms, and speed of disease progression. Diagnosis requires loss of function in both upper and lower motor neurons for limb- and bulbar-onset ALS, distinguishing ALS from other neuromuscular diseases. Although no cause or initial trigger has been determined for ALS, eventually both limb and bulbar muscles will show dysfunction as the disease progresses. In later stages of the disease, muscle dysfunction typically leads to respiratory failure and death. Management of neurotransmitter levels in patients can prolong life by months, but no cure exits for the disease. Other treatments exist that can help patients manage muscle weakness or spasms as the disease progresses. The book concludes by considering future detection, treatment, and diagnostic approaches with the goal of preventing disease initiation or progression.Human diseases and conditions collection.Amyotrophic lateral sclerosisAmyotrophic Lateral SclerosisLibros electronicos.amyotrophic lateral sclerosis (ALS)Lou Gehrig's diseasemotor neuron diseaseneuromuscular junctionlimb-onset ALSbulbar-onset ALSmuscle weaknessAmyotrophic lateral sclerosis.Amyotrophic Lateral Sclerosis.616.83Miller Mary E.940760FINmELBFINmELBBOOK9910136584103321Nerve disease ALS and gradual loss of muscle function2121485UNINA