03117nam 2200589 450 991013628430332120230621140739.09782889193097(ebook)(CKB)3710000000586898(SSID)ssj0001684392(PQKBManifestationID)16517248(PQKBTitleCode)TC0001684392(PQKBWorkID)15045384(PQKB)10315505(WaSeSS)IndRDA00056744(oapen)https://directory.doabooks.org/handle/20.500.12854/54886(EXLCZ)99371000000058689820160829d2014 uy |engur||#||||||||txtrdacontentcrdamediacrrdacarrierNovel roles of non-coding brain RNAs in health and disease /topic editor: Hermona SoreqFrontiers Media SA2014France :Frontiers Media SA,20141 online resource (213 pages) illustrations; digital, PDF file(s)Frontiers Research TopicsBibliographic Level Mode of Issuance: MonographIncludes bibliographical references.Non-coding RNAs (ncRNAs), and in particular microRNAs are rapidly becoming the focus of research interest in numerous basic and translational fields, and their importance for many aspects in brain functioning merits special discussion. The wide-scope, multi-targeted and highly efficient manner of ncRNA regulatory activities draws attention to this topic by many, but the available research tools and experimental protocols are still insufficient, and their importance for many aspects in brain functioning merits special discussion. This Research Topic is focused on the search for and exploration of those non-coding RNAs whose activities modulate the multi-levelled functions of the eukaryotic brain. It will strive to cover novel approaches for identifying and establishing ncRNA-target relationships, reports of the affected pathways, inherited and acquired changes in ncRNA functioning and the use of ncRNA mimics and blockade tools for interference with their functions in health and disease. Non-coding RNAs are here to stay, and their impact on our brain’s functioning at the physiology, cell biology, behaviour and immune levels is worth an in-depth journey.Animal BiochemistryHILCCHuman Anatomy & PhysiologyHILCCHealth & Biological SciencesHILCCCentral Nervous SystemMicroRNAsEpilepsySchizophreniacholinergic signalinglong non-coding RNAsAlzheimerischemic strokeAnimal BiochemistryHuman Anatomy & PhysiologyHealth & Biological SciencesHermona Soreqauth1365342Soreq H.PQKBUkMaJRU9910136284303321Novel roles of non-coding brain RNAs in health and disease3387151UNINA