03606nam 2200697 450 991013628100332120230621141347.0(CKB)3710000000586910(SSID)ssj0001684432(PQKBManifestationID)16517428(PQKBTitleCode)TC0001684432(PQKBWorkID)15045162(PQKB)10274698(WaSeSS)IndRDA00056919(oapen)https://directory.doabooks.org/handle/20.500.12854/55362(EXLCZ)99371000000058691020160829d2015 fy 0engur||#||||||||txtrdacontentcrdamediacrrdacarrierThe oral microbiome in an ecological perspective /edited by Egija Zaura and Alex MiraFrontiers Media SA2015[Lausanne, Switzerland] :Frontiers Media SA,[2015]©20151 online resource (116 pages) illustrations; digital file(s)Frontiers Research Topics,1664-8714Bibliographic Level Mode of Issuance: Monograph"Published in: Frontiers in cellular and infection microbiology" -- front cover.Print version: 2889195767 Includes bibliographical references.The oral cavity harbors an immense diversity of microorganisms, including bacteria, fungi, archaea, protozoa and viruses. At health, oral microbial community is thought to be in a state of homeostasis, even after numerous perturbations (e.g., toothbrushing, food intake) a day. The breach in this homeostasis can occur for instance if the perturbations become too excessive (e.g., frequent carbohydrate intake leading to acidification of the community) or the host is compromised (e.g., inadequate immune response resulting in persistent inflammation of periodontal tissue). Aggressive antimicrobial therapy (e.g., antibiotics in case of periodontal disease or preventive antibiotic therapy before and after dental extractions) is commonly applied with all the negative consequences of this approach. So far little is known on the interplay between the environmental, host and microbial factors in maintaining an ecological balance. What are the prerequisites for a healthy oral ecosystem? Can we restore an unbalanced oral microbiome? How stable is the oral microbiome through time and how robust it is to external perturbations? Gaining new insights in the ecological factors sustaining oral health will lead to conceptually new therapies and preventive programs.Frontiers research topics.Quorum sensing (Microbiology)Communicable diseasesMicrobiology & ImmunologyHILCCBiologyHILCCHealth & Biological SciencesHILCCOral ecologyQuorum SensingImmune SystemmetatranscriptomicsBiofilmhorizontal gene transferFungal bacterial interactionsDental PlaqueQuorum sensing (Microbiology)Communicable diseases.Microbiology & ImmunologyBiologyHealth & Biological SciencesEgija Zauraauth1364865Mira AlexZaura Egija1971-PQKBUkMaJRUBOOK9910136281003321The oral microbiome in an ecological perspective3386308UNINA