03060nam 2200625 450 991013627780332120230621140718.09782889194445(ebook)(CKB)3710000000586921(SSID)ssj0001680358(PQKBManifestationID)16496335(PQKBTitleCode)TC0001680358(PQKBWorkID)15028414(PQKB)10175611(WaSeSS)IndRDA00056381(oapen)https://directory.doabooks.org/handle/20.500.12854/53766(EXLCZ)99371000000058692120160829d2015 uy 0engur||#||||||||txtrdacontentcrdamediacrrdacarrierModels and estimation of genetic effects /topic editors : José M. Álvarez-Castro and Rong-Cai YangFrontiers Media SA2015France :Frontiers Media SA,20151 online resource (99 pages) illustrations; digital, PDF file(s)Frontiers Research TopicsBibliographic Level Mode of Issuance: MonographIncludes bibliographical references.Ronald Fisher needed to develop elaborate models of genetic effects in order to set the foundations of Quantitative Genetics in his 1918 paper “The correlation between relatives on the supposition of Mendelian inheritance”. Since then, many significant implementations have been made to model genetic effects. However, at the verge of one century after Fisher’s kick-off, models of genetic effects keep on being discussed and implemented. Indeed, the relatively recent advent of QTL analyses challenged the state of the art of this field by providing researchers the opportunity to obtain and analyse estimates of genetic effects from real data. In this context, the development of this field was not exempt of some polemics, like the debate about the convenience of the functional and the statistical epistasis approaches. This research topic is meant to provide recent developments in models of genetic effects and to enrich the discussion about how and why models of genetic effects must be further developed and applied.GeneticsHILCCBiologyHILCCHealth & Biological SciencesHILCCsimulation studiesHost-Pathogen Interactionsstatistical estimationGenetic architecturemathematical modellingimprintinggene-by-environment interactionsgene mappingEpistasisGenetic EffectsGeneticsBiologyHealth & Biological SciencesRong-Cai Yangauth1366250Álvarez-Castro José MYang Rong-CaiPQKBUkMaJRU9910136277803321Models and estimation of genetic effects3388734UNINA