05020nam 2200661 450 991013234920332120230807212049.01-118-46870-81-118-46875-9(CKB)3710000000252412(EBL)1813087(OCoLC)893332546(SSID)ssj0001374372(PQKBManifestationID)11915349(PQKBTitleCode)TC0001374372(PQKBWorkID)11326511(PQKB)11490017(MiAaPQ)EBC1813087(Au-PeEL)EBL1813087(CaPaEBR)ebr10952044(CaONFJC)MIL650888(EXLCZ)99371000000025241220141018h20152015 uy 0engurcnu||||||||txtccrCancer and its management /Jeffrey Tobias, Daniel HochhauserSeventh edition.Chichester, England ;Oxford, England ;Hoboken, New Jersey :Wiley Blackwell,2015.©20151 online resource (627 p.)Description based upon print version of record.1-322-19608-7 1-118-46873-2 Includes bibliographical references at the end of each chapters and index.""Cover""; ""Title Page""; ""Copyright""; ""Contents""; ""Preface""; ""Acknowledgements""; ""Abbreviations""; ""Chapter 1 The modern management of cancer: an introductory note""; ""References""; ""Further reading""; ""Chapter 2 Epidemiology, cure, treatment trials and screening""; ""Terminology and methods in epidemiology""""Geographical distribution of cancer""""Temporal distribution of cancer""; ""Causes of cancer suggested by epidemiological studies""; ""Inhaled carcinogens""; ""Lifestyle and diet""; ""Ionizing irradiation""; ""Occupational factors""; ""Viral causes""; ""Cancer statistics""; ""Survival data and determination of cure in cancer""; ""Assessment of results: trials of treatment""; ""Randomized trials""; ""Informed consent""; ""Non-randomized studies of treatment""; ""Screening for cancer""; ""Secondary prevention of cancer""; ""References""; ""Further reading""""Chapter 3 Biology of cancer""""Carcinogenesis: persistent genetic damage""; ""Chemical carcinogens""; ""Ionizing and ultraviolet irradiation""; ""Initiators and promoters in carcinogenesis""; ""Repair of damage to DNA induced by carcinogens""; ""Inherited defects involving DNA damage or repair processes that predispose to cancer""; ""Viral causes of cancer""; ""RNA viruses""; ""DNA viruses""; ""Cellular oncogenes""; ""Tumour-suppressor genetic mechanisms in cancer development""; ""Cell division""; ""Inheritance of cancer""""Clonal origin, progression and growth of a cancer""""Monoclonality and heterogeneity in cancer""; ""The growth of cancer""; ""Differentiation in cancer""; ""Invasion, angiogenesis and metastasis""; ""Tumour immunology""; ""Immune responses to cancer""; ""Monoclonal antibodies""; ""Reference""; ""Further reading""; ""Chapter 4 Staging of tumours""; ""Staging notation""; ""The primary tumour (T)""; ""Lymph node involvement (N)""; ""Presence of metastases (M)""; ""Staging techniques""; ""Ultrasound""; ""Computed tomography""; ""Magnetic resonance imaging""""Isotope scanning""""Positron emission tomography""; ""Diagnosis of specific metastatic sites""; ""Pulmonary metastases""; ""Bone metastases""; ""Hepatic metastases""; ""Brain metastases""; ""The role of surgery in diagnosis and staging""; ""Tumour markers""; ""Human chorionic gonadotrophin""; ""Î Fetoprotein""; ""Placental alkaline phosphatase""; ""Carcinoembryonic antigen""; ""CA-125""; ""CA-19-9""; ""Molecular staging of cancer""; ""References""; ""Further reading""; ""Chapter 5 Radiotherapy ""; ""Sources and production of ionizing radiation""""Radioactive isotopes""Now in its seventh edition, this highly-regarded book is designed as an introductory and reference text on the principles of diagnosis, staging, and treatment of tumors. As for the last 6 editions of the book, the aim and scope of the new edition are once again to provide a thorough yet reasonably brief account of the whole field of oncology, focusing on the latest principles of cancer management. The book is already well established, having been first published in 1986 and in continuous print since then. The authors are rightfully proud of their strong legacy of providing carefully revisedCancerTreatmentCancerDiagnosisCancerTreatment.CancerDiagnosis.616.99/4Tobias Jeffrey872762Hochhauser DanielMiAaPQMiAaPQMiAaPQBOOK9910132349203321Cancer and its management1948442UNINA