05398nam 2200685 450 991013225870332120220506142442.01-118-38767-81-118-38765-11-118-38768-6(CKB)3710000000371597(EBL)1895437(SSID)ssj0001436799(PQKBManifestationID)11799435(PQKBTitleCode)TC0001436799(PQKBWorkID)11443090(PQKB)11660749(MiAaPQ)EBC1895437(DLC) 2014038298(Au-PeEL)EBL1895437(CaPaEBR)ebr11030441(CaONFJC)MIL769815(OCoLC)906183038(PPN)204519144(EXLCZ)99371000000037159720150320h20152015 uy 0engur|n|---|||||txtccrInternational textbook of diabetes mellitus /editors-in-chief Ralph A. DeFronzo [and three others]Fourth edition.Chichester, England :Wiley Blackwell,2015.©20151 online resource (1203 p.)Description based upon print version of record.0-470-65861-4 Includes bibliographical references at the end of each chapters and index.Cover; Contents; Contributors; Preface; Section I Epidemiology; Chapter 1 Classification of diabetes mellitus and other categories of glucose intolerance; Introduction; Historical perspective and current classifications; Previous classifications; Current classification; Type 1 process; Type 2 process; Other specific types; Classification of genetic disorders; Genetic defects of β-cell function; Genetic defects in insulin action; Diseases of the exocrine pancreas; Endocrinopathies; Drug-or chemical-induced diabetes; Infections; Uncommon but specific forms of immune-mediated diabetes mellitusOther genetic syndromes associated with diabetesDiabetes in children and youth; Diagnosis of diabetes using HbA1c; Diagnosis of gestational diabetes mellitus; Impaired glucose regulation (impaired glucose tolerance and impaired fasting glycemia); Normoglycemia; Summary; References; Chapter 2 Epidemiology and risk factors for type 1 diabetes mellitus; Introduction; Prevalence and incidence; Geographic location; Race and ethnicity; Age and gender; Increasing incidence and seasonality; β-Cell autoimmunity and risk factors; Family history of T1DM; HLA class II susceptibility genotypesOther genetic factors associated with type 1 diabetesIslet autoantibodies; Autoantibody screening among relatives; Autoantibody screening in the general population; Measurement of autoantibodies in adult-onset diabetes; Measurement of β-cell function; Environmental factors; Gene-environment interaction in clinical type 1 diabetes; Established type 1 diabetes; Clinical onset; Remission (honeymoon period); Acute complications; Morbidity and mortality; References; Chapter 3 Epidemiology and geography of type 2 diabetes mellitusAge- and sex-specific prevalence of type 2 diabetes in different ethnic groupsDiagnostic criteria for diabetes; Conversion factors for glucose concentrations; Age- and sex-specific plasma glucose concentration; Age- and sex-specific prevalence of diabetes; Previously undiagnosed diabetes; Prevalence of impaired glucose tolerance and impaired fasting glycemia in different ethnic groups; Europe; Asia; Sex differences in prevalence of diabetes, IGT, and IFG; The ratio of IGT to diabetes; Secular trends in prevalence of type 2 diabetes; Type 2 diabetes in children; Prevalence and incidenceCharacteristics and diagnosisRisk factors; Complications and comorbid conditions; Modifiable risk factors for type 2 diabetes; Obesity; Physical activity; Dietary factors; Nontraditional modifiable risk factors for type 2 diabetes; Inflammation; Smoking; References; Section II Physiology of pancreatic function; Chapter 4 Development and maintenance of the islet β cell; Introduction; Pancreas development; Induction of the definitive endoderm; Patterning of the gut tube into organ domains; Induction of the dorsal and ventral pancreatic budsPancreatic growth and epithelial branching morphogenesisThe International Textbook of Diabetes Mellitus has been a successful, well-respected medical textbook for almost 20 years, over 3 editions. Encyclopaedic and international in scope, the textbook covers all aspects of diabetes ensuring a truly multidisciplinary and global approach. Sections covered include epidemiology, diagnosis, pathogenesis, management and complications of diabetes and public health issues worldwide. It incorporates a vast amount of new data regarding the scientific understanding and clinical management of this disease, with each new edition always reflecting thDiabetesPopular worksDiabetisthubLlibres electrònicsthubDiabetesDiabetis616.4/62DeFronzo Ralph A.MiAaPQMiAaPQMiAaPQBOOK9910132258703321International textbook of diabetes mellitus2026195UNINA