05468nam 2200673 450 991013225620332120200520144314.03-527-67341-53-527-67342-33-527-67339-3(CKB)3710000000355746(EBL)1953329(OCoLC)903357111(SSID)ssj0001467518(PQKBManifestationID)11872175(PQKBTitleCode)TC0001467518(PQKBWorkID)11518381(PQKB)10430308(MiAaPQ)EBC1953329(Au-PeEL)EBL1953329(CaPaEBR)ebr11019995(CaONFJC)MIL729454(PPN)19558290X(EXLCZ)99371000000035574620150226h20152015 uy 0engur|n|---|||||txtccrAnalyzing biomolecular interactions by mass spectrometry /edited by Jeroen Kool and Wilfried M. A. NiessenWeinheim, Germany :Wiley-VCH Verlag GmbH & Co.,2015.©20151 online resource (403 p.)Description based upon print version of record.1-322-98172-8 3-527-33464-5 Includes bibliographical references and index.""Analyzing Biomolecular Interactions by Mass Spectrometry""; ""Contents ""; ""List of Contributors ""; ""Preface ""; ""Abbreviations ""; ""Chapter 1 Introduction to Mass Spectrometry, a Tutorial ""; ""1.1 Introduction ""; ""1.2 Figures of Merit ""; ""1.2.1 Introduction ""; ""1.2.2 Resolution ""; ""1.2.3 Mass Accuracy """"1.2.4 General Data Acquisition in MS """"1.3 Analyte Ionization ""; ""1.3.1 Introduction ""; ""1.3.2 Electrospray Ionization ""; ""1.3.3 Matrix-Assisted Laser Desorption Ionization ""; ""1.3.4 Other Ionization Methods ""; ""1.3.5 Solvent and Sample Compatibility Issues """"1.4 Mass Analyzer Building Blocks """"1.4.1 Introduction ""; ""1.4.2 Quadrupole Mass Analyzer ""; ""1.4.3 Ion-Trap Mass Analyzer ""; ""1.4.4 Time-of-Flight Mass Analyzer ""; ""1.4.5 Fourier Transform Ion Cyclotron Resonance Mass Spectrometer ""; ""1.4.6 Orbitrap Mass Analyzer """"1.4.7 Ion Detection """"1.5 Tandem Mass Spectrometry ""; ""1.5.1 Introduction: ""Tandem-in-Time"" and ""Tandem-in-Space"" ""; ""1.5.2 Ion Dissociation Techniques ""; ""1.5.3 Tandem Quadrupole MS-MS Instruments ""; ""1.5.4 Ion-Trap MS n Instruments ""; ""1.5.5 Tandem TOF (TOF-TOF) Instruments """"1.5.6 Hybrid Instruments (Q-TOF, Q-LIT, IT-TOF) """"1.5.7 MS-MS and MSn in FT-ICR-MS ""; ""1.5.8 Orbitrap-Based Hybrid Systems ""; ""1.5.9 Ion-Mobility Spectrometry-Mass Spectrometry ""; ""1.6 Data Interpretation and Analytical Strategies ""; ""1.6.1 Data Acquisition in MS Revisited """"1.6.2 Quantitative Bioanalysis and Residue Analysis ""This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomiBiomoleculesAnalysisChemistry, AnalyticQuantitativeBiomoleculesAnalysis.Chemistry, AnalyticQuantitative.572.33Kool JeroenNiessen Wilfried M. A.MiAaPQMiAaPQMiAaPQBOOK9910132256203321Analyzing biomolecular interactions by mass spectrometry2171077UNINA03535nam 2200685Ia 450 991096864120332120251117115240.01-135-71555-61-138-18035-11-135-71556-41-280-10991-20-203-45432-410.4324/9780203454329 (CKB)111087027782426(EBL)178755(OCoLC)299569928(SSID)ssj0000121015(PQKBManifestationID)11142643(PQKBTitleCode)TC0000121015(PQKBWorkID)10092447(PQKB)11680788(MiAaPQ)EBC178755(Au-PeEL)EBL178755(CaPaEBR)ebr10058018(CaONFJC)MIL10991(OCoLC)52479823(EXLCZ)9911108702778242619970203d1997 uy 0engur|n|---|||||txtccrChildren and their curriculum the perspectives of primary and elementary school children /edited by Andrew Pollard, Dennis Thiessen, and Ann Filer1st ed.London ;Washington, D.C. Falmer Press19971 online resource (215 p.)Description based upon print version of record.0-203-26145-3 0-7507-0594-9 Includes bibliographical references and index.Book Cover; Title; Contents; Acknowledgments; Introduction: New Challenges in Taking Children's Curricular Perspectives Seriously; Pupils, Teachers and the Ownership of Curriculum Knowledge: Editors' Introduction; The Relevance of Creative Teaching: Pupils' Views; The Tale of a Task: Learning Beyond the Map; Pupils' Lives and the Curriculum as Lived Experience: Editors' Introduction; Shared and Negotiated Territories: The Socio-cultural Embeddedness of Children's Acts of Meaning; 'At Least They Were Laughing': Assessment and the Functions of Children's Language in Their 'News' SessionWithdrawal, Resistance and Adaptation in Shaping the Experienced Curriculum: Editors' IntroductionThe Politics of Primaries: The Micropolitical Perspectives of 7-Year-Olds; Experience through the Eyes of Quiet Bird: Reconnecting Personal Life and School Life; Methodological Challenges: Editors' Introduction; Observing Children on a School Playground: The Pedagogics of Child-watching; In Search of Authenticity: Researching Young Children's Perspectives; Knowing about, Acting on Behalf of, and Working with Primary Pupils' Perspectives: Three Levels of Engagement with ResearchNotes on ContributorsIndexThe aim of this text is to encourage educators and researchers in recognizing pupil perspectives. Its central argument is that understanding some of the disparity between ""curriculum as intended"" and ""curriculum as experienced"" will increase the quality of school life and improve learning.Education, ElementaryCurriculaGreat BritainEducation, PrimaryCurriculaEducation, ElementaryCurriculaEducation, PrimaryCurricula.372.19Pollard Andrew1949-61711Thiessen Dennis1877803Filer Ann1705192MiAaPQMiAaPQMiAaPQBOOK9910968641203321Children and their curriculum4490223UNINA