03599nam 2200613 450 991013223030332120230803201931.01-118-39626-X1-118-39629-41-118-39627-8(CKB)3710000000093473(EBL)1650820(SSID)ssj0001132598(PQKBManifestationID)11592085(PQKBTitleCode)TC0001132598(PQKBWorkID)11154812(PQKB)11292197(MiAaPQ)EBC4388567(DLC) 2014001135(MiAaPQ)EBC1650820(Au-PeEL)EBL1650820(CaPaEBR)ebr10849275(OCoLC)868150760(EXLCZ)99371000000009347320140327h20142014 uy 0engur|n|---|||||txtccrMolecular aspects of aging understanding lung aging /edited by Mauricio Rojas, Silke Meiners, Claude Jourdan LeSauxHoboken, New Jersey :Wiley-Blackwell,2014.©20141 online resource (231 p.)Description based upon print version of record.1-118-39624-3 Includes bibliographical references at the end of each chapters and index.The demography of aging / David E. Bloom and Sinead Shannon -- The "OMICS" of aging : insights from genomes upon stress / Ismene Karakasilioti, Anna Ioannidou, and George A. Garinis -- Protein quality control coming of age / Silke Meiners -- Telomerase function in aging / Rodrigo T. Calado -- The cellular senescence progtam / Pooja Shivshankar and Claude Jourdan Lesaux -- Signaling networks controlling cellular senescence / Leena P. Desar, Yan Y. Sanders, and Victor J. Thannickal -- Immune senescence / Kevin P. High -- Developmental and physiological aging of the lung / Kent E. Pinkerton, Lei Wang, Suzette M. Smiley-Jewell, Jingyi Xu, and Francis H. Y. Green -- Mouse models to explore the aging lung / Mingyi Wang and Deepak A. Deshpande -- Evidence for premature lung aging of the injured neonatal lung as exemplified by bronchopulmonary dysplasia / Anne Hilgenderff -- Remodeling of the extracellular matrix in the aging lung / Jesse Roman -- Aging Mesenchymal Stem Cells in lung disease / Maria G. Kapetanaki, Ana L. Mora, and Mauricio Rojas -- COPD as a disease of premature aging / Laurent Boyer, Jorge Boczkowski, and Serge Adnot -- Lung infections and aging / Jacqueline M. Kehler and Keith C. Meyer.Molecular Aspects of Aging: Understanding Lung Aging covers recent research in the mechanisms that contribute to cellular senescence. Covering universal themes in aging, such as the exhaustion of stem cells and subsequent loss of the regenerative refueling of organs as well as immunosenescence, this text illuminates new directions for research not yet explored in the still poorly investigated area of molecular mechanisms of lung aging. The molecular nature of general aging processes is explored with targeted coverage on how to analyze lung aging through experimental approaches.AgingPhysiologyLungsDiseasesAgingPhysiology.LungsDiseases.612.6/7Rojas Mauricio1963-Meiners SilkeLe Saux Claude JourdanMiAaPQMiAaPQMiAaPQBOOK9910132230303321Molecular aspects of aging2042249UNINA